Lapatinib Ditosylate Monohydrate CAS 388082-78-8 Purity >99.0% (HPLC)

Whakaahuatanga Poto:

Ingoa matū: Lapatinib Ditosylate Monohydrate

CAS: 388082-78-8

Maamaa: >99.0% (HPLC)

Te ahua: Kowhai Kowhai ki te Paura Tioata Kowhai

Whakapā: Takuta Alvin Huang

Pūkoro/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Hua e Pa ana

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Lapatinib Intermediates:

Ngā Āhuatanga matū:

Ingoa matū Lapatinib Ditosylate Monohydrate
Nga kupu taurite N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
Tau CAS 388082-78-8
Tūnga Taonga Kei roto i nga taonga
Tātai rāpoi C29H26ClFN4O4S·2(C7H8O3S)·H2O
Taumaha rāpoi 943.48
COA & MSDS Kei te waatea
Taketake Shanghai, Haina
Waitohu Ruifu Chemical

Whakatakotoranga:

Tūemi Whakatakotoranga
Te ahua Kowhai Kowhai ki te Paura Tioata Kowhai
Te Maama / Tikanga Tatauria ≥99.0% (HPLC)
Iwi Whakarewa 240.0~242.0℃
makuku (KF) 1.9~2.4%
Te poke kotahi ≤0.50%
Nga poke katoa ≤1.00%
Konga Taamaha (hei Pb) ≤20ppm
Paerewa Whakamatau Paerewa hinonga
Whakamahinga API;Mo te maimoatanga o nga turoro me te mate pukupuku uma

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku

Painga:

1

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388082-78-8 - Taupānga:

Ko te Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) te tote ditosylate oCAS 231277-92-2, he quinazoline waihanga, mahi-waha me te mahi antineoplastic pea.Ka whakakorea e ia te phosphorylation o te epidermal growth factor receptor (EGFR), ErbB2, me nga Erk-1 me-2 me AKT kinases;ka aukati hoki i nga taumata pūmua cyclin D i roto i nga raina pūtau puku tangata me nga xenografts.Ko te EGFR me te ErbB2 kua uru ki te tipu o nga momo pukupuku.I whakarewahia mo te maimoatanga o te HER2 (ErbB2) te mate pukupuku u pai i roto i nga wahine kua whiwhi maimoatanga o mua.I kitea te tarukino ka whakawhanakehia e GlaxoSmithKline.

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