Apixaban Intermediate CAS 545445-44-1 Purity >98.0% (HPLC)
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua o 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one (CAS: 545445 -44-1) me te kounga teitei, te takawaenga o Apixaban (CAS: 503612-47-3).Ka taea e Ruifu Chemical te tuku i te ao, te utu whakataetae, te ratonga pai, te iti me te rahinga e waatea ana.Hokona nga Apixaban Intermediates,Please contact: alvin@ruifuchem.com
| Ingoa matū | 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one |
| Nga kupu taurite | Apixaban Intermediate 1;5,6-Dihydro-3-(4-Morpholinyl)-1-[4-(2-Oxo-1-Piperidinyl)phenyl]-2(1H)-Pyridinone;5-Morpholin-4-yl-1-[4-(2-Oxopiperidin-1-yl)phenyl]-2,3-Dihydropyridin-6-one;Apixaban poke A |
| Tūnga Taonga | I roto i te Stock, Production Arumoni |
| Tau CAS | 545445-44-1 |
| Tātai rāpoi | C20H25N3O3 |
| Taumaha rāpoi | 355.43 g/mol |
| Iwi Whakarewa | >199℃(tikuri) |
| Kiato | 1.267 g/mL |
| COA & MSDS | Kei te waatea |
| Taketake | Shanghai, Haina |
| Kāwai | Takawaenga o Apixaban (CAS: 503612-47-3) |
| Waitohu | Ruifu Chemical |
| Nga taonga | Whakatakotoranga | Hua |
| Te ahua | Paura Kōwhai Maama | Paura Kōwhai Maama |
| Ngaronga i te whakamaroke | <0.50% | 0.16% |
| Te toenga i runga i te mura | <0.20% | 0.07% |
| Te Maama / Tikanga Tatauria | >98.0% (HPLC Area) | 99.12% |
| Te poke takitahi | <0.50% | <0.50% |
| Nga poke katoa | <2.00% | 0.88% |
| 1H NMR Spectrum | E rite ana ki te Hanganga | Ka rite |
| LC-MS mo te Tautuhinga | Ka rite | Ka rite |
| Whakamutunga | Kua whakamatauria te hua me te whai ki nga whakaritenga kua tohua | |
| Taupānga | Takawaenga o Apixaban (CAS: 503612-47-3) | |
Mōkī:Pounamu Fluorinated, Peeke pepa konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
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Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Ko te 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one (CAS: 545445-44-1) he takawaenga o Apixaban (CAS: 503612-47-3).
Ko Apixaban he momo hou o te aukati take Xa-waha i hangaia e Bristol-Myers Squibb me Pfizer.Ko te ingoa hokohoko ko Eratol, he momo hou o te rongoa o-waha.Na roto i te aukati i tetahi take nui o te coagulation Xa, ka taea e Apixaban te aukati i te hanga thrombin me te thrombosis.I te Paenga-whāwhā 26, 2007, i hono atu a Bristol-Myers Squibb ki a Pfizer ki te whakapuaki i te mahi tahi ki te whakawhanaketanga o te Apixaban anticoagulant waha hou na Bristol-Myers Squibb hei whakakapi mo Warfarin.I te marama o Haratua 2011, ko Apixaban te tuatahi ki te whakaae ki te aukati i te thrombosis venous i roto i nga turoro pakeke e mahi ana i nga mahi whakakapi hipoki, turi ranei i roto i nga whenua 27 EU, Iceland me Norway.I te Whiringa-a-rangi 20, 2012, i whakaaetia e te Komihana a te Pakeha a Ererto (Apixaban) mo te aukati i te whiu me te embolism pūnaha i roto i nga turoro pakeke me te kore-valvular atrial fibrillation (NVAF) me te kotahi, neke atu ranei nga mea morearea.I muri mai, ka whakaaetia e te Canadian Food and Drug Administration, Japan, me te US FDA a Ererto (Apixaban) mo te aukati i te whiu me te embolism pūnaha i roto i nga turoro pakeke me te kore-valvular atrial fibrillation (NVAF) me te kotahi, neke atu ranei nga mea morearea.I te Paenga-whāwhā 12, 2013, ko te rongoa anticoagulant hou Eloto (ELIQUIS)(Apixaban) i hangaia tahitia e Bristol-Myers Squibb me Pfizer i panuitia kia whakarārangihia ki Haina.
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