5-Amino-3-(Trifluoromethyl)picolinonitrile CAS 573762-62-6 Apalutamide Intermediate Purity >98.0% (HPLC)
Ko Shanghai Ruifu Chemical Co., Ltd te kaihanga matua o 5-Amino-3-(Trifluoromethyl)picolinonitrile (CAS: 573762-62-6) me te kounga teitei, te takawaenga o Apalutamide (CAS: 956104-40-8).Ka taea e Ruifu Chemical te tuku i te ao, te utu whakataetae, te ratonga pai, te iti me te rahinga e waatea ana.Hokona nga Takawaenga Apalutamide,Please contact: alvin@ruifuchem.com
| Ingoa matū | 5-Amino-3-(Trifluoromethyl)picolinonitrile |
| Nga kupu taurite | 5-Amino-3-(Trifluoromethyl)pyridine-2-Carbonitrile;5-Amino-3-(Trifluoromethyl)2-Cyanopyridine;5-Amino-2-Cyano-3-(Trifluoromethyl)pyridine;Apalutamide poke 10 |
| Tūnga Taonga | I roto i te Stock, Production Arumoni |
| Tau CAS | 573762-62-6 |
| Tātai rāpoi | C7H4F3N3 |
| Taumaha rāpoi | 187.12 g/mol |
| Kiato | 1.45±0.10 g/cm3 |
| COA & MSDS | Kei te waatea |
| Taketake | Shanghai, Haina |
| Te akomanga morearea | 6.1 |
| Roopu Tarapi | Ⅲ |
| Kāwai | Takawaenga o Apalutamide (CAS: 956104-40-8) |
| Waitohu | Ruifu Chemical |
| Nga taonga | Nga Paerewa Tirotiro | Hua |
| Te ahua | Kōwhai Kōwhai ki te Mārō Kōwhai | Ka tutuki |
| Wai na Karl Fischer | <0.50% | 0.35% |
| Te Maama / Tikanga Tatauria | >98.0% (HPLC) | 99.03% |
| Spectrum Infrared | E rite ana ki te Hanganga | Ka tutuki |
| 1H NMR Spectrum | E rite ana ki te Hanganga | Ka tutuki |
| Whakamutunga | Kua whakamatauria te hua me te whai ki nga whakaritenga kua tohua | |
| Taupānga | Takawaenga o Apalutamide (CAS: 956104-40-8) | |
Mōkī:Pounamu Fluorinated, Peeke pepa konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Kia kati tonu te ipu ka penapena ki roto i te whare putunga hauhautanga, maroke me te hau pai kia matara atu i nga matū hotokore.Tiaki i te marama me te makuku.
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Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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KoungaWhakapumautanga?Pūnaha whakahaere kounga tino.Ko nga taputapu ngaio mo te tātari ko te NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Tauira?Ko te nuinga o nga hua e whakarato ana i nga tauira kore utu mo te aromatawai kounga, me utu nga utu kaipuke e nga kaihoko.
Te arotake a wheketere?Nau mai te arotake wheketere.Whakaritea he hui i mua.
MOQ?Kaore he MOQ.Ka whakaaetia te ota iti.
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Te kawe waka?Ma te Express (FedEx, DHL), ma te Air, ma te Moana.
Tuhinga?I muri i te ratonga hokohoko: COA, MOA, ROS, MSDS, me etahi atu ka taea te whakarato.
Whakaritenga Whakaritenga?Ka taea te whakarato ratonga whakahiato ritenga kia pai ai to hiahia rangahau.
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Ko te 5-Amino-3-(Trifluoromethyl)picolinonitrile (CAS: 573762-62-6), he pyridine heterocyclic organic compound, ka taea te whakamahi hei takawaenga rongoa.Ko te 5-Amino-3-(Trifluoromethyl)picolinonitrile he takawaenga o Apalutamide (CAS: 956104-40-8).Ko te Apalutamide he antiandrogen whakatipuranga tuarua e whakamahia ana mo te maimoatanga o te mate pukupuku prostate.He kaitukino kaha o te kaiwhakawhiwhi androgen me te uara IC50 o te 16 nM.Ka herea nga kaiwhakawhiwhi androgen, na reira ka aukati i te whakawhiti karihi, te herenga DNA me te whakakorikori tuhinga.Ko te Apalutamide he rongoa rongoa mo te mate pukupuku prostate kore-metastatic, he aukati i te castration.
Ka whakamahia te Apalutamide ki te rongoa i etahi momo mate pukupuku prostate-atete ki te maka, mate pukupuku prostate ranei kaore i horapa ki etahi atu waahanga o te tinana, engari kaore i awhinahia e etahi atu rongoa.Ko te Apalutamide kei roto i te karaehe rongoa e kiia nei ko te aukati kaikawe androgen.Ka mahi ma te aukati i nga paanga o te androgen hei aukati i te tipu me te horapa o nga pūtau mate pukupuku.I te Hepetema 17, 2019, i whakaaetia e te Whakahaere Kai me te Taakaro a Apalutamide (ERLEADA, Janssen Biotech, Inc) mo nga turoro me te mate pukupuku mate pukupuku mate pukupuku metastatic castration-tairongo (mCSPC).I whakamanahia a Apalutamide i te tau 2018 mo nga turoro he mate pukupuku prostate kore-metastatic castration-aukati.
