Trelagliptin Succinate Intermediate CAS 865759-24-6 Purity >98.0% (HPLC)
Tauranga Aromoni Trelagliptin Succinate Takawaenga e Pa ana:
6-Chloro-3-Methyluracil CAS 4318-56-3
2-Cyano-5-Flurobenzyl Bromide CAS 421552-12-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
Trelagliptin Succinate Intermediate-int D CAS 865759-24-6
Trelagliptin Succinate CAS 1029877-94-8
Please contact: alvin@ruifuchem.com
Ingoa matū | Trelagliptin Succinate Intermediate-int D |
Nga kupu taurite | 2-((6-Chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile;2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-4-fluorobenzonitrile |
poke | Trelagliptin poke 17 |
Tūnga Taonga | Kei roto i nga taonga, Tauine Aromoni |
Tau CAS | 865759-24-6 |
Tātai rāpoi | C13H9ClFN3O2 |
Taumaha rāpoi | 293.68 g/mol |
Kiato | 1.49±0.10 g/cm3 |
Rokiroki Temp. | Wahi Matao me te maroke |
COA & MSDS | Kei te waatea |
Waitohu | Ruifu Chemical |
Nga taonga | Nga Paerewa Tirotiro | Hua |
Te ahua | Maama-Ma ki te Kiriata Kowhai Maama | Ka rite |
Tautuhinga | ||
HPLC | Ko te wa pupuri o te tauira whakamatautau te tihi nui ka tutuki ki te paerewa tohutoro | Ka rite |
IR - Awhiowhio Infrared | He rite te ahua o te tauira me te paerewa whakaurunga IR | Ka rite |
Te tirotiro | ||
Ngaronga i te whakamaroke | <0.50% | 0.3% |
Nga poke katoa | <2.00% | Ka rite |
Te Maama / Tikanga Tatauria | >98.0% (HPLC) | 99.1% |
Whakamutunga | Kua whakamatauria te hua me te whai ki nga whakaritenga |
Mōkī:Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Rokiroki i roto i nga ipu hiri i te whare putunga makariri me te maroke me te hau pai kia matara atu i nga matū hotokore.Tiaki i te marama me te makuku.A ape i te marama;Kati hau.
Tukunga:Tukuna ki te ao ma te FedEx / DHL Express.Whakaratohia te tuku tere me te pono.
Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 tau te wheako?Neke atu i te 15 tau o matou wheako ki te hanga me te kaweake i te whānuitanga o nga momo takawaenga rongoa kounga teitei, matū pai ranei.
Nga maakete matua?Hokona ki te maakete kaainga, Amerika Te Tai Tokerau, Uropi, Inia, Korea, Hapani, Ahitereiria, aha atu.
Nga painga?Ko te kounga teitei, te utu utu, nga ratonga ngaio me te tautoko hangarau, te tuku tere.
KoungaWhakapumautanga?Pūnaha whakahaere kounga tino.Ko nga taputapu ngaio mo te tātari ko te NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Tauira?Ko te nuinga o nga hua e whakarato ana i nga tauira kore utu mo te aromatawai kounga, me utu nga utu kaipuke e nga kaihoko.
Te arotake a wheketere?Nau mai te arotake wheketere.Whakaritea he hui i mua.
MOQ?Kaore he MOQ.Ka whakaaetia te ota iti.
Wā Tukunga? Mena kei roto i nga taonga, e toru nga ra ka whakamanahia te tuku.
Te kawe waka?Ma te Express (FedEx, DHL), ma te Air, ma te Moana.
Tuhinga?I muri i te ratonga hokohoko: COA, MOA, ROS, MSDS, me etahi atu ka taea te whakarato.
Whakaritenga Whakaritenga?Ka taea te whakarato ratonga whakahiato ritenga kia pai ai to hiahia rangahau.
Nga tikanga utu?Ko te nama Proforma ka tukuna tuatahi i muri i te whakapumautanga o te ota, ka kohia o maatau korero peeke.Te utu ma te T/T (Telex Transfer), PayPal, Western Union, etc.
2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile (CAS: 865759-24-6) ka whakamahia hei takawaenga o Trelagliptin Succinate (CAS: 1029877-94-8).Ko te Trelagliptin Succinate, i whakawhanakehia e Takeda, Japan, i whakarewahia i te Maehe 2015, i raro i te ingoa hokohoko Zafatek, ka whakamahia ki te rongoa i te mate huka momo 2.Ko te Trelagliptin he aukati i te dipeptidyl peptidase IV (DPP-4) te roa e mahi ana ma te whiriwhiri me te aukati tonu i te DPP-4 hei whakahaere i nga taumata huka toto.Ko te Trelagliptin te rongoa hypoglycemic tuatahi i ia wiki i runga i te maakete, a me tango nga momo aukati DPP-4 i runga i te maakete kotahi i ia ra.Ko nga painga o te rongoa Zafatek ka kore e kore e pai ake nga whiringa maimoatanga mo nga turoro mate huka.Ko te tumanako ka tino whakapai ake i te waatea me te whakatutukitanga o nga turoro.i runga i te Maehe 26, 2015, i kii a Takeda a Takeda ko te rongoa mate huka hou a Zafatek i whakaaetia e te Manatu o Hapani mo te hauora, mahi me te oranga (MHLW) mo te maimoatanga o te mate huka momo 2.Ko te whakaaetanga e tohu ana ko Zafatek te rongoa hypoglycemic a-waha tuatahi mo ia wiki i runga i te maakete o te ao, me te tohu ano hoki i te poraka i tukuna e Takeda i te maakete mate huka.
Ko te Trelagliptin he aukati dipeptidyl peptidase IV (DPP-4) kotahi wiki ia wiki e whakahaere ana i nga taumata huka toto ma te maataki me te aukati tonu i te DPP-4.Ko te DPP-4 he whākōkī e taea ai te kōkiri i te incretin (glucagon-like peptide -1 (GLP-1) me te glucose-dependent insulinotropic polypeptide (GIP)), e whai wāhi nui ana ki te whakahaere i te huka toto.Ko te aukati i te DPP-4 ka nui ake te huka toto e whakawhirinaki ana ki te whakamaarama o te insulin, na reira ka whakahaere i te taumata huka toto.Ko te tukunga Trelagliptin NDA i ahu mai i nga korero whaihua me te haumaru mai i nga whakamatautau haumanu i te wahanga III i whakahaerehia i nga turoro o Hapani me te mate huka momo 2.Ko te kaha o te Trelagliptin kua whakapumautia i roto i nga whakamatautau katoa, he pai te haumaru me te manawanui.Ko te Whakahaere Trelagliptin kotahi i te wiki ka taea te whakahaere pai i te taumata huka toto me te tumanako ka pai ake te whakatutukitanga o nga rongoa a nga turoro.