Cyano-Irbesartan CAS 138401-24-8 Purity >98.0% (HPLC) Irbesartan Intermediate Factory
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Ingoa matū | Cyano-Irbesartan |
Nga kupu taurite | CyanoIrbesartan;Irbesartan Cyano poke;Irbesartan Hydrocarbon;Irbesartan poke 6;2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]kore-1-en-4-one;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4]kore-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile |
Tau CAS | 138401-24-8 |
Tau CAT | RF-PI1892 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C25H27N3O |
Taumaha rāpoi | 385.51 |
Kiato | 1.15 |
Wairewa (Warewa ki roto) | Mewaro |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki tata ma te paura ki te kiriata |
Te Maama / Tikanga Tatauria | >98.0% (HPLC) |
Maamaa | >97.0% (Me te Nitrogen Tapeke) |
Te Whakarewa | 91.0 ki te 95.0 ℃ |
Ngaronga i te whakamaroke | <1.00% |
Te poke kotahi | <1.00% |
Nga Korewa Taamaha | <20ppm |
Spectrum Infrared | He rite ki te Hanganga |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga / Parakore o Irbesartan (CAS: 138402-11-6) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko Cyano-Irbesartan (CAS: 138401-24-8) he takawaenga, poke ranei o Irbesartan (CAS: 138402-11-6).Ko te Irbesartan he angiotensin II (Angiotensin II, Ang II) te aukati i te kaikawe.Kua wehea nga kaiwhakawhiwhi Angiotensin II ki nga momo e rua: AT1 me AT2.Ka aukati a Irbesartan i te kaikawe AT1 o AnglI.Ka taea e ia te aukati i te huringa o Ang ki Ang, ka taea te whakahē i te angiotensin-converting enzyme 1 receptor (AT1).Ko te antagonistic antagonistic i runga i te AT1 he 8500 wa atu i te AT2.Ka taea e ia te aukati i te herenga o te Ang me te kaiawhina AT1 na roto i te aukati i te aukati vasoconstriction me te tuku aldosterone, ka puta he paanga hypotensive.Karekau tenei hua e aukati i te angiotensin converting enzyme (ACE), renin, etahi atu kaiwhakawhiwhi taiaki, kaore hoki e aukati i nga awa katote e pa ana ki te whakaritenga o te pehanga toto me te toenga konutai.Ka taea hoki e Irbesartan te whakaheke i te whakarereketanga hiko o te myocardium, na reira ka whakahekehia te mate o nga turoro me te whakaheke toto.I tenei wa ko te rongoa tino whai hua mo te maimoatanga o te whakaheke toto me nga mate cardiovascular.