Dantrolene Sodium Salt Hydrate CAS 14663-23-1 API Factory Kounga Teitei
Whakarato me te Maama me te Kounga Pumau
Ingoa matū: Dantrolene Sodium Salt Hydrate
CAS: 14663-23-1
Whakangao Ngauaua Koiwi.Kaakawaenga Channel Inhibitor
API Kounga Teitei, Hanganga Tauhokohoko
Ingoa matū | Dantrolene Sodium Salt Hydrate |
Nga kupu taurite | 1-[5-(4-Nitrophenyl)furfurylideneamino]hydantoin Sodium Tote Hydrate |
Tau CAS | 14663-23-1 |
Tau CAT | RF-API78 |
Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
Tātai rāpoi | C14H11N4NaO5 |
Taumaha rāpoi | 338.25 |
Wairewa | Wairewa i roto i te DMSO |
Tikanga Tukunga | Ka tukuna i raro i te pāmahana ambient |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Kowhai-Karaka ki te Karaka Tioata Paura.Karekau he taunakitanga e kitea ana mo te poke i nga mea ke |
Tautuhi A | Te IR Absorption (197K) |
Tautuhinga B | Ko te wa pupuri o te tihi nui i roto i te chromatogram o te whakarite whakamatautau e rite ana ki tera i roto i te chromatogram o te whakaritenga paerewa, i riro mai i te whakamatautau |
Tautuhinga C | Ka tutuki nga whakaritenga o te whakamatautau mura mo te Konutai (191) |
Tautuhinga D | Wāhanga 1: Ka puta mai he rewharewha puhoi, ma, kirikiriata Wāhanga 2: Kare te rerenga e ngaro Wāhanga 3: Ka memeha katoa te rerenga Wāhanga 4: Karekau he rerenga i hanga |
Ihirangi Wai (na KF) | 14.5%~17.0% |
Rahi Matūriki | 90% iti iho i te 200um |
Te whakamatautau | 90.0%~96.0% o C14H10N405 i runga i te tikanga kore |
Nga Taonga Paanga | (HPLC, Rohe%) |
Pūhui Pātahi A | ≤0.15% |
Pūhui Pānga B | ≤0.50% |
Pūhui Pātahi C | ≤0.30% |
Wairewa toenga | |
Ewaro | ≤2000ppm |
Mewaro | ≤2000ppm |
Acetone | ≤2000ppm |
DMF | ≤620ppm |
Nga Korewa Taamaha | ≤10ppm |
Te Ora Papa | 2 Tau |
Paerewa Whakamatau | United States Pharmacopoeia (USP) |
Whakamahinga | Whakangao Ngauaua Koiwi.Kaakawaenga Channel Inhibitor |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko te Dantrolene Sodium Salt Hydrate (CAS 14663-23-1), he aukati ngota ngota iti o te kaitukino kaiawhina a Ryanodine me te aukati hongere Calcium.Ko te Tote konutai Dantrolene he mea whakangawari i nga uaua koiwi, e aukati ana i te tukunga Ca 2+-roto-roto mai i te reticulum sarcoplasmic.Ko te aukati o te tukunga Ca2+ mai i te reticulum sarcoendoplasmic, e tino pa ana ki te whakaihiihi me te whakahekenga o nga uaua, ka whakaputa i te awe whakangao uaua e hono ana ki te Dantrolene.Ko te neurotoxicity e whakaatuhia ana e te mahi glutamate kua whakahuahia e hono ana ki te pikinga nui o nga taumata Ca2+ cytoplasmic, me te tohu a Dantrolene hei kaihoko neuroprotective ki te neurotrasmitter-induced excitotoxicity.Ko te Dantrolene, te Tote konutai he aukati o RyR-1 me RyR-3.