Darunavir CAS 206361-99-1 Purity Anti-HIV Purity ≥99.0% API High Purity HIV Protease Inhibitor
Kaihanga KaihangaNga Hua e Pa ana ki a Darunavir:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Ingoa matū | Darunavir |
| Nga kupu taurite | TMC114;UIC-94017 |
| Tau CAS | 206361-99-1 |
| Tau CAT | RF-API68 |
| Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
| Tātai rāpoi | C27H37N3O7S |
| Taumaha rāpoi | 547.66 |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Te Paura Maama, Maama-Ma ranei |
| Tautuhinga | MS/HNMR HPLC |
| Wairewa | Wairewa i roto i te DMSO, He iti te wairewa ki te wai |
| Iwi Whakarewa | 74.0~76.0℃ |
| Tautuhinga | 1H NMR |
| Te Maama / Tikanga Tatauria | ≥99.0% (HPLC) |
| Nga Taonga Paanga | |
| Max Single poke | ≤0.30% |
| Nga poke katoa | ≤1.0% |
| Wairewa toenga | Ewaro ≤0.30% |
| Ngaronga i te whakamaroke | ≤0.50% |
| Te toenga i runga i te mura | ≤0.10% |
| Nga Korewa Taamaha | ≤20ppm |
| Arsenic | ≤1.5ppm |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor Anti-HIV |
Mōkī: Pounamu, Peeke konumohe konumohe, Paera Kaata, 25kg / Paera, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko Darunavir (te ingoa tohu Prezista, i mohiotia i mua ko TMC114) he rongoa aukati protease e whakamahia ana hei rongoa i te mate HIV.Ko te Darunavir he whiringa maimoatanga e taunakitia ana e te OARAC mo nga pakeke me nga taiohi kua mohio ki te maimoatanga-kore me te maimoatanga.Ko Darunavir he momo hou o te aukati protease anti retroviral kore peptide i roto i te rongoa AIDS.I whakawhanakehia tuatahi e te peka ho'oraa a Johnson, Tibotec.Ko te tino pai o te koiora i roto i nga aukati protease 6 (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir me ABT378/r).Ka mahi ma te aukati i te hanganga o nga matūriki huaketo hou me te pakeke mai i te mata o nga pūtau kaihautu kua pangia me te aukati i te porotease o te huaketo.Ka whakamahia te hua mo te wa roa, ka taea e ia te whakaheke i te mate huaketo HIV i roto i te toto, te whakanui ake i te tatau o nga pūtau CD4, te whakaheke i te tupono o te mate HIV, te whakapai ake i te kounga o te ora me te roa o te ora.He pai mo nga pakeke kua pangia e te mate HIV engari karekau he painga ki te whakamahi i nga raau taero antiretroviral.Me whakakotahi te rongoa me te whakamahi i nga pota iti o te ritonavir me etahi atu raau taero antiretroviral, kia pai ake ai te whai hua.Ka taea te arotake i te mahi antiviral in vitro ma te aukati i nga lymphocytes pangia me nga lymphocytes i roto i te toto peripheral.
