Waikawa Diethylphosphonoacetic CAS 3095-95-2 Purity >99.5% (HPLC) Afatinib Dimaleate Intermediate Factory
Ruifu Chemical Supply Takawaenga o Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Waikawa Diethylphosphonoacetic CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-kotahi CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5
Ingoa matū | Waikawa Diethylphosphonoacetic |
Nga kupu taurite | 2-(Diethoxyphosphoryl)Acetic Waikawa;(Diethoxyphosphinyl)Acetic Waikawa;Diethyl Carboxymethylphosphonate;NSC 272281 |
Tau CAS | 3095-95-2 |
Tau CAT | RF-PI2024 |
Tūnga Taonga | I roto i te Raarangi, Te Whakaputa Whakaputa 30MT/Marama |
Tātai rāpoi | (C2H5O)2P(O)CH2CO2H |
Taumaha rāpoi | 196.14 |
Kohuatanga | 150 ℃/0.05 mmHg (marama) |
Kiato | 1.220 g/mL i te 25 ℃ (marama) |
Taurangi Refactive | n20/D 1.445 (marama) |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Wai Taekore |
Tautuhi (HPLC) | Ko te wa pupuri o te tihi matua ka riro mai i te tauira kei roto i te 5% o te tauira tohutoro. |
Te Maama / Tikanga Tatauria | >99.5% (HPLC) |
Spectrum Infrared | He rite ki te Hanganga |
Proton NMR Spectrum | He rite ki te Hanganga |
makuku (KF) | <0.50% |
Nga poke katoa | <0.50% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Afatinib Dimaleate (CAS: 850140-73-7) |
Mōkī: Pounamu Fluorinated, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
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Diethylphosphonoacetic Acid (CAS: 3095-95-2), Ka mahi hei nucleophile mo nga tauhohenga taapiri nucleophilic mo te whakahiato o nga epoxide allene Reactant mo: Nga rangahau stereoselectivity o te tauhohenga a Staudinger;Ko te hanganga enantioselective o nga diols na roto i te epoxidation me te hydration tauhohenga;Horner-Wadsworth-Emmons tauhohenga;Kei te whakahaeretia e te chelation mamao a Ireland-Claisen te whakatikatika;Ko nga tauhohenga Ugi-Dieckmann mo te whakahiatotanga o nga paheketanga waikawa tetramic;I whakamahia hei hanga takawaenga phosphonoester mo nga tauhohenga HEW intramolecular.Ko te Diethylphosphonoacetic Acid he takawaenga o Afatinib Dimaleate (CAS: 850140-73-7).I whakaaetia a Afatinib Dimaleate e te US Food and Drug Administration (FDA) i te tau 2013 mo te maimoatanga o te mate pukupuku mate pukupuku kore-iti (NSCLC).Ko te mea motuhake, i whakaaetia mo nga turoro e mau ana i nga pukupuku NSCLC metastatic kei roto i te epidermal growth factor receptor (EGFR) exon deleted exon 21 ranei.Ko te Afatinib Dimaleate he kaitao whakakorikori o te ErbB tyrosine kinases (tyk), e whakaheke ana i te tohu ErbB ma te herenga korekore o nga waahi here EGFR tyk.
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Waikawa Diethylphosphonoacetic CAS 3095-95-2 Purit...
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