Diflorasone Diacetate CAS 33564-31-7 Assay 97.0~103.0% Factory Corticosteroid

Diflorasone Diacetate [33564-31-7]
» Ko te Diflorasone Diacetate he iti iho i te 97.0 paiheneti, kaua hoki e neke ake i te 103.0 paiheneti o C26H32F2O7, kua tatauhia i runga i te whakamaroke.
Packaging me te rokiroki-Tiaki i roto i nga ipu kiki.
Paerewa Tohutoro USP <11>-
USP Diflorasone Diacetate RS
Te Tautuhinga, Te Kohanga Infrared <197M>.
Te hurihanga motuhake <781S>: i waenganui i +58° me +68°.Te otinga whakamatautau: 20 mg, kaore i whakamarokehia, mo ia mL, ki te chloroform.
Ngaronga i runga i te whakamaroke <731>-Me whakamaroke ki te korehau i te 60 ° me te pehanga kaua e neke ake i te 5 mm o te mer cury mo nga haora 16: ka ngaro te 0.5% o tona taumaha.
Te toenga i te mura <281>: kaua e neke ake i te 0.5%
Pure Chromatographic-
Waahanga pūkoro me te punaha Chromatographic-Whakaritea kia rite ki te tohutohu i roto i te Assay.
Wairewa Whakamatau-Whakarewahia te rahinga tika o te Diflorasone Diacetate i roto i te chloroform kua kukū ki te wai kia whiwhi ai i te otinga he 6 mg ia mL te kukū.
Tikanga-Tukuhia he rōrahi (tata ki te 10 µL) o te otinga Whakamātautau ki roto i te chromatograph, tuhia te chromatogram mo te wa e rite ana ki te 5 wa te wa pupuri o te tihi nui, ka ine i nga waahi o nga tihi katoa.Tātaihia te ōrau o ia poke i te wahanga o te Diflorasone Diacetate i tangohia e te tauira:
100(ri / rs)
kei te ri ko te waahi teitei mo ia poke;a ko te rs te tapeke o nga waahi o nga tihi katoa: kaua e neke ake i te 1.0% o nga poke takitahi ka kitea;a kaua e neke ake i te 2.0% o nga poke katoa ka kitea.
whakamātautau-
Wāhanga pūkoro-Whakaritea he otinga kei roto he ranunga o te n-butyl chloride, te methylene chloride, te waikawa acetic glacial, me te tetrahydrofuran (350:125:15:10).Whakaritea nga whakarereketanga mehemea e tika ana (tirohia te Whakaaetanga Pūnaha i raro i te Chromatography <621>).
Wairewa paerewa o roto-Ma te whakamahi i te chloroform kukū-wai, whakarite he otinga o te acetate isoflupredone kei roto e pā ana ki te 0.04 mg ia mL.
Whakariterite Paerewa-Warekahia te rahinga tika o te USP Diflorasone Diacetate RS i roto i te otinga paerewa o roto kia whiwhi ai i tetahi otinga e mohiotia ana mo te 33µg ia mL.
Te whakarite whakamatautau-Whakawhitihia mo te 15 mg o Diflorasone Diacetate, i tika te pauna, ki te 500-mL pounamu rōrahi.Tāpirihia te otinga paerewa o roto ki te rōrahi, ka uru.
Pūnaha Chromatographic (tirohia te Chromatography <621>)-Ko te chromatograph wai he taputapu ki te 254-nm kaitahuri me te 4.6-mm × 10-cm tīwae kei roto 3- µm tarapi L3.Ko te tere rere he 2.5 mL ia meneti.Chromatograph te Whakariterite Paerewa, ka tuhi i nga waahi tihi e kiia ana mo te Tikanga: ko te taumira, R, i waenga i te tātari me nga tihi paerewa o roto kaua e iti iho i te 12;me te inenga paerewa mo te iti iho i te wha nga werohanga tukurua kaua e neke ake i te 2.0%.
Tikanga-Tukuhia wehe nga pukapuka rite (e tata ana ki te 10 µL) o te whakaritenga Paerewa me te whakareri Assay ki te chromatograph, tuhia nga chromatograms, me te ine i nga waahi mo nga tihi nui.Ko nga wa e pupuri ana mo te 1.0 mo te diflorasone diacetate me te 2.4 mo te paerewa o roto.Tātaihia te rahinga, i te mg, o C 26H32F2O7 i te wahanga o te Diflorasone Diacetate i tangohia e te tauira:
0.5C(RU / RS)
ko C te kukū, i roto i te µg ia mL, o te USP Diflorasone Diacetate RS i roto i te whakaritenga Paerewa;me te RU me te RS ko nga owehenga o nga waahi teitei mo te Diflorasone Diacetate me nga waahi paerewa o roto i whiwhi mai i te whakaritenga Assay me te Whakaritea Paerewa, ia.