EDC·HCl CAS 25952-53-8 Hononga Reagent Pure >99.0% (T) wheketere
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua o 1-(3-Dimethylaminopropyl) -3-Ethylcarbodiimide Hydrochloride (EDC·HCl) (CAS: 25952-53-8) me te kounga teitei.Ka tukuna e Ruifu Chemical he raupapa o nga reagents tiaki me nga reagents hono.Ka taea e Ruifu te tuku i te ao, te utu whakataetae, te iti me te rahinga e waatea ana.Hoko EDC·HCl,Please contact: alvin@ruifuchem.com
Ingoa matū | 1-(3-Dimethylaminopropyl)-3-Ethylcarbodiimide Hydrochloride |
Nga kupu taurite | EDC·HCl;EDAC·HCl;EDCI·HCl;EDC Hydrochloride;EDAC Hydrochloride;N-(3-Dimethylaminopropyl)-N′-Ethylcarbodiimide Hydrochloride;1-Ethyl-3-(3-Dimethylaminopropyl)carbodiimide Hydrochloride;N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide Hydrochloride;Waiwai Wairewa Carbodiimide |
Tūnga Taonga | I roto i te Stock, Production Mass |
Tau CAS | 25952-53-8 |
Tātai rāpoi | C8H17N3·HCl |
Taumaha rāpoi | 191.70 g/mol |
Iwi Whakarewa | 110.0~115.0℃ |
Kiato | 0.877 g/mL i te 20 ℃(marama) |
Taupū Refactive n20/D | 1.461 |
Rokiroki i raro i te Hau Inert | Rokiroki i raro i te Hau Inert |
Tairongo | Hygroscopic.Te makuku, te wera |
Wairewa wai | Tino Wairewa ki te wai |
Wairewa | Wairewa ki te Dimethylformamide, Waipiro |
Rokiroki Temp. | Wahi Matao me te maroke (<5 ℃) |
COA & MSDS | Kei te waatea |
Kāwai | Tauhohenga Hononga |
Waitohu | Ruifu Chemical |
Nga taonga | Nga Paerewa Tirotiro | Hua |
Te ahua | Paura Tioata Ma | Ka tutuki |
Iwi Whakarewa | 110.0~115.0℃ | 112.0~114.0℃ |
Wai na Karl Fischer | <0.50% | 0.10% |
Te toenga i runga i te mura | <0.10% | 0.04% |
Pure (Argentmetric Titration) | >99.0% | 99.70% |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) | Ka tutuki |
Spectrum Infrared | He rite ki te Hanganga | Ka tutuki |
Wairewa i roto i te H2O (100 mg/mL) | Korekore ki te Tino Kowhai Kowhai, Maama | Paahi |
Whakamutunga | Kua whakamatauria te hua me te whai ki nga whakaritenga kua tohua |
Mōkī:Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Makuku Tairongo.Rokiroki i roto i nga ipu hiri ki te whare putunga makariri me te maroke (<5 ℃) kia matara atu i nga matū hotokore.Tiaki i te marama me te makuku.
Tukunga:Tukuna ki te ao ma te FedEx / DHL Express.Whakaratohia te tuku tere me te pono.
Āhuatanga: Ko tenei hua he paura tioata ma.
2. Whakaritenga Ihirangi:
2.1 Nga taputapu me nga reagents: titrator potentiometric, wairewa waikawa nitric (12.5 wt%), otinga paerewa AgNO3 (0.1mol/L)
2.2 Tauira whakarite me te mahi:
Ko te 200 ki te 220mg i rewa ki te 40ml o te wai maturu, a, i muri i te taapiri 5ml o te wairewa waikawa nitric, ko te otinga he mea whakarewa noa ki te pakawa hiriwa.
I titrated te wai ki te pito mutunga.Ko te tikanga mo te tatau i te ihirangi hua e whai ake nei:
X = (VAgNO3*19.171)/W,
X- Ko te ōrau o te EDC.HCl, 100%.
V-Ko te rōrahi i pau i te otinga paerewa AgNO3, ml
19.171-1ml AgNO3 otinga paerewa (0.1mol / L) pau EDC.HCl papatipu, mg;
W - tauira papatipu, mg;
Ko te tikanga i mahia e toru nga wa i roto i te whakarara, ka tangohia te toharite, me te hapa kia kaua e neke atu i te 0.3%.Ko te ihirangi hua kia> 99.0%.
3. Ira whakarewa: kia rite ki te tikanga whakatau ira whakakoero (Appendix VII C o Chinese Pharmacopoeia 2010 putanga), kia 110.0~115.0 ℃ te rewa o tenei hua.
4. Te whakatau i te ihirangi wai: kia rite ki te tikanga ine makuku (tikanga KF) hei whakatau, ko te ihirangi wai o tenei hua kia <0.50%.
5. Rokiroki: Rokiroki ki tetahi wahi maroke pouri me te hauhautanga (<5 ℃).
6. Te wa arotake: kotahi tau
Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 tau te wheako?Neke atu i te 15 tau o matou wheako ki te hanga me te kaweake i te whānuitanga o nga momo takawaenga rongoa kounga teitei, matū pai ranei.
Nga maakete matua?Hokona ki te maakete kaainga, Amerika Te Tai Tokerau, Uropi, Inia, Korea, Hapani, Ahitereiria, aha atu.
Nga painga?Ko te kounga teitei, te utu utu, nga ratonga ngaio me te tautoko hangarau, te tuku tere.
KoungaWhakapumautanga?Pūnaha whakahaere kounga tino.Ko nga taputapu ngaio mo te tātari ko te NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Tauira?Ko te nuinga o nga hua e whakarato ana i nga tauira kore utu mo te aromatawai kounga, me utu nga utu kaipuke e nga kaihoko.
Te arotake a wheketere?Nau mai te arotake wheketere.Whakaritea he hui i mua.
MOQ?Kaore he MOQ.Ka whakaaetia te ota iti.
Wā Tukunga? Mena kei roto i nga taonga, e toru nga ra ka whakamanahia te tuku.
Te kawe waka?Ma te Express (FedEx, DHL), ma te Air, ma te Moana.
Tuhinga?I muri i te ratonga hokohoko: COA, MOA, ROS, MSDS, me etahi atu ka taea te whakarato.
Whakaritenga Whakaritenga?Ka taea te whakarato ratonga whakahiato ritenga kia pai ai to hiahia rangahau.
Nga tikanga utu?Ko te nama Proforma ka tukuna tuatahi i muri i te whakapumautanga o te ota, ka kohia o maatau korero peeke.Te utu ma te T/T (Telex Transfer), PayPal, Western Union, etc.
Waehere Morearea
R34 - He weranga
R36/37/38 - He whakapataritari ki nga kanohi, te punaha manawa me te kiri.
R41 - He kino kino ki nga kanohi
R37/38 - He whakapataritari ki te punaha manawa me te kiri.
R20/21/22 - He kino ma te horomia, ka pa ki te kiri me te horomia.
Whakaahuatanga Haumaru
S26 - Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora.
S36/37/39 - Mau kakahu whakamarumaru tika, karapu me te whakamarumaru kanohi/kanohi.
S45 - Ki te aituā, ki te kore koe e pai, rapua he tohutohu hauora (whakaatuhia te tapanga ina taea.)
S37/39 - Kia mau nga karapu tika me te whakamarumaru kanohi/kanohi
S36 - Mau kakahu whakamarumaru tika.
UN ID UN 2735 8/PG 3
WGK Tiamana 3
RTECS FF2200000
FLUKA BRAND F CODES 1-3-10
TSCA Y
Waehere HS 2925290090
Tohu Whakamate
Te paitini LD50 i roto i te kiore: 56mg/kg
Ko te 1-(3-Dimethylaminopropyl)-3-Ethylcarbodiimide Hydrochloride (EDC·HCl) (CAS: 25952-53-8) he paura tioata ma, he ngawari te whakaheke, he memeha ki te wai, he wairewa i roto i te waihano, whakamahia hei tauhohenga whakahoaho mo te carboxyl. Ko nga roopu i roto i te amide synthesis, ka whakamahia ano mo te whakahohe i nga roopu phosphate, te honohono-whiti o nga pūmua me nga waikawa nucleic, me te hanga o nga immunocouplers.Ka whakamahia te EDC-HCl i roto i te awhe pH o 4.0-6.0 me te whakamahi i te nuinga o te waa me te N-Hydroxysuccinimide (NHS) me te N-Hydroxysulfosuccinimide konutai tote hei whakapai ake i te pai o te hono.
Ko te EDC·HCl he carbodiimide wairewa-wai, e whakamahia nuitia ana mo te hononga peptide.Ka whakamahia te EDC·HCl hei kaihoko whakakorikori carboxyl.He mahi nui mo te aukati i nga koiora nui i roto i te hononga ki te N-hydroxysuccinimide.Ka whakamahia ano ki te acylation o phosphoranes.
Ko te wai-wairewa o te carbodiimide e whai hua ana mo te whakakotahi i te haptens ki nga pūmua me nga polypeptides.Ka whakamahia ki te whakarereke i nga kaiwhakawhiwhi NMDA me te mea he maatete whakamaarama i roto i te whakahiato peptide.Ko te painga nui o te hononga EDAC he ngawari te tango i te reagent taikaha me te Urea e rite ana ma te horoi ki te waikawa waimeha, ki te wai ranei.Ko nga Carbodiimides ka whakakorikori i te hanganga o nga here amide, te waikawa carboxylic, me nga amine ma te whakahohe i te carboxylate ki te hanga i te O-acylurea.Ka taea e tenei takawaenga te whakaeke tika e te amine ki te hanga i te amide.Ka tukuna te EDAC hei pärönaki urea wairewa.
Ka taea te whakamahi EDC·HCl mo te whakahiato o nga amides.Ka whakamahia hei kaihoko hono i roto i te whakahiatotanga o nga esters mai i nga waikawa carboxylic ma te whakamahi i te dimethylaminopyridine hei whakakorikori.
Ko te nuinga o nga mea e toru e whakamahia nuitia ana i te toha: DCC, DIC me EDC·HCl.Ko te whakamahi i tenei momo o te maatete whakaahuru i te nuinga o te waa e hiahia ana ki te taapiri i nga whakakorikori acylation, nga kaiwhakaoho ranei, penei i te DMAP, HOBt, me etahi atu. karekau e whakamahia te catalyst ki te huri ki te ester hohe e rite ana, ki te amide kaha ranei, ka huri ano ki te hua-a-urea e rite ana ki te Urea (Ara B).Whakahohenga whakakorikori: Ko nga momo e whai ake nei o te kaiwhakaoho whakakorikori e whakamahia nuitia ana.I tenei wa, kua whakamahia nuitia te 4-N,N-dimethylpyridine (DMAP) ki te whakakoi i nga momo tauhohenga acylation.I etahi wa ka taea te whakamahi i te 4-PPY i te mea kaore i te pai te awe o te DMAP.E ai ki nga tuhinga e tika ana, ko tona kaha catalytic he tata ki te mano nga wa teitei ake i te DMAP.i roto i nga condenser e toru e whakamahia nuitia ana, he iti ake te DCC me te DIC.Ko te tikanga ka whakamahia tahi te DCC me te DMAP.Ko tetahi o nga ngoikoretanga nui o te whakamahi i te DCC ko tetahi atu hua o te tauhohenga, te dicyclohexylurea, he iti te whakarewatanga i roto i te waahanga kaiao whanui engari he iti te wairewa, na reira he uaua ki te tango tino ma roto i etahi tikanga purenga e whakamahia nuitia ana, recrystallization, tīwae chromatography, etc.;na te mea he iti te whakarewatanga o te dicyclohexylurea i roto i te ether i etahi atu whakarewa, no reira, ko te maimoatanga o tenei momo tauhohenga ka whakaeto i te whakarewa tauhohenga me te taapiri i te ether, me te tātari i te nuinga o te dicyclohexylurea i mua i etahi atu maimoatanga.Na te mea he pai ake te whakarewatanga o te diisopropylurea i hangaia e DIC i roto i nga whakarewa pararopi whanui, ka whakamahia i roto i te matū matū whakahiato-waahanga whakahiato.Kei te whakamahia te EDCI i tenei wa i roto i te matū rongoa.Ko tetahi o ona ahuatanga matua ko te Urea i hangaia i muri i te tauhohenga he wairewa-wai, he ngawari ki te horoi atu.Ko te tikanga, ka honoa te EDCI me te HOBt (whakatupato: he mea tino nui tenei tauhohenga HOBt, ki te kore he iti rawa te tukunga o te kondensation).I etahi wa mena he nui te aukati o te waikawa, he roopu tango irahiko ranei, ka noho te tauhohenga ki te hikoi ester hohe (he kaha te tohu awhiowhio a te ester kaha, ka kitea e MS, LC-MS ranei).