Entecavir Monohydrate CAS 209216-23-9 API wheketere Te Kounga Teitei Antiviral Hepatitis B Infection Whakaahua Whakaatu

Entecavir Monohydrate CAS 209216-23-9 wheketere API Te Kounga Teitei Te Waahanga Paatete B Antiviral

Whakaahuatanga Poto:

Ingoa matū: Entecavir Monohydrate

CAS: 209216-23-9

Te ahua: Paura ma, tata ranei ma te kirikiriata

Ko te rongoa pareketo e whakamahia ana mo te maimoatanga o te mate Hepatitis B

API Kounga Teitei, Hanganga Tauhokohoko

Inquiry: alvin@ruifuchem.com

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Whakaahuatanga:

Ko te Kaihanga Kaihanga me te Maama me te Kounga Pumau
Ingoa matū: Entecavir Monohydrate
CAS: 209216-23-9
Ka whakamahia mo te maimoatanga o te mate Hepatitis B
API Kounga Teitei, Hanganga Tauhokohoko

Ngā Āhuatanga matū:

Ingoa matū	Entecavir Monohydrate
Nga kupu taurite	Entecavir Hydrate;9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]guanine Monohydrate
Tau CAS	209216-23-9
Tau CAT	RF-API79
Tūnga Taonga	Kei roto i nga taonga, ka eke ki te rau kirokaramu
Tātai rāpoi	C12H17N5O4
Taumaha rāpoi	295.3
Iwi Whakarewa	>220℃
Kiato	1.81
Tikanga Tukunga	Ka tukuna i raro i te pāmahana ambient
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Paura ma, tata ma ranei te kirikiriata
Wairewa	Ka Rere noa i roto i te Dimethylformamide, He iti te Rere ki te Wai, te Ewaro me te Mewaro
Tautuhinga IR	He rite te hihinga o te tauira ki te paerewa tohutoro
Tautuhinga HPLC	Ko te wa pupuri o te tauira whakamatautau ka rite ki tera o te paerewa tohutoro
Ihirangi Wai (na KF)	5.5%~6.5%
Hurihanga Optical Tauwhāiti	+24.0° ki te +30.0° (DMF: MeOH=1:1 C=1%) (i runga i te matū waikore)
Te toenga i runga i te mura	≤0.10%
Nga Taonga Paanga
Furoentecavir	≤0.10%
Entecavir 1-Epimer	≤0.10%
Entecavir 3-Epimer	≤0.10%
8-Methyoxy Entecavir	≤0.10%
Entecavir 4-Epimer	≤0.10%
8-Hydroxy Entecavir	≤0.10%
4-Dimethylsilyl Entecavir	≤0.10%
Entecavir Related Compound A	≤0.10%
Tetahi poke kore i tohua	≤0.10%
Nga poke katoa	≤0.30%
Wairewa toenga
Mewaro	≤600ppm
Dichloromethane	≤300ppm
Ethyl Acetate	≤1000ppm
Tetrahydrofuran	≤720ppm
Toluene	≤890ppm
Benzyl Chloride	≤1000ppm
Benzyl Alcohol	≤1000ppm
Tepe Microbial
Tatau Aerobic Tapeke	≤100cfu/g
Rewena me nga Maaka	≤10cfu/g
Escherichia Coli	Kaua e kitea
Nga Korewa Taamaha	≤10ppm
Te whakamatautau	98.0%~102.0% (HPLC; i runga i te tikanga anhydrous)
Rahi Matūriki	95% o nga matūriki me noho i roto i te 125um
Paerewa Whakamatau	Paerewa hinonga;United States Pharmacopoeia (USP) Paerewa
Whakamahinga	Ko te rongoa pareketo e whakamahia ana mo te maimoatanga o te mate Hepatitis B

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.

Painga:

FAQ:

Taupānga:

Ko te Entecavir Monohydrate (CAS 209216-23-9) he rongoa parepare-a-waha e whakamahia ana hei rongoa i te mate Hepatitis B Virus (HBV).Ko te Entecavir Monohydrate he tairitenga nucleoside (he mea nui ake, he tairitenga guanine) e aukati ana i te whakamaoritanga whakamuri, te tukurua DNA me te tuhi i roto i te vira.He momo hou o nga raau taero cyclopentyl acyl guanosine anti-Hepatitis B me ona hua rongoa rite ki te Entecavir.Ka whakamahia e te haumanu ki te maimoatanga o te mate Hepatitis B pakeke e kaha ana te tukuruatanga viral, te pikinga o te serum transaminase ALT, nga reinga kaha ranei i kitea mai i te hitori o te ate.Ko te Entecavir Monohydrate he aukati kaha me te whiriwhiri o te HBV, me te EC50 o 3.75 nM i roto i te HepG2 pūtau.Ko te Entecavir he aukati transcriptase whakamuri.Ka aukati i te Hepatitis B Virus (HBV) mai i te tini me te whakaiti i te nui o te huaketo i roto i te tinana.