Erlotinib Hydrochloride CAS 183319-69-9 Purity >99.0% (HPLC)

Whakaahuatanga Poto:

Ingoa matū: Erlotinib Hydrochloride

Nga kupu taurite: Erlotinib HCl;Tarceva

CAS: 183319-69-9

Pure (HPLC): >99.0%

Te ahua: Ma ki te Paura Tioataata-Ma

Whakapā: Takuta Alvin Huang

Pūkoro/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Whakaahuatanga:

Kaihanga rangatira me te kaiwhakarato o Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one CAS 179688-29-0
Please contact: alvin@ruifuchem.com

Ngā Āhuatanga matū:

Ingoa matū	Erlotinib Hydrochloride
Nga kupu taurite	Erlotinib HCl;Tarceva;CP-358774 Hydrochloride;6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline Hydrochloride;N-(3-Ethynylphe nyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine HCl
Tau CAS	183319-69-9
Tau CAT	RF-PI2242
Tūnga Taonga	I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi	C22H24ClN3O4
Taumaha rāpoi	429.90
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Ma ki te Paura Tioata-White
Tautuhinga	A: IR: Whakautu ki te Tohu Tohutoro B: HPLC: Whakautu ki te Tohutoro RT
Wairewa	He iti rawa te whakarewa i roto i te wai, he iti te wairewa i te methanol me te koretake i roto i te Acetonitrile, Acetone, Ethyl Acetate me te Hexane
Iwi Whakarewa	223.0~229.0 ℃
Ngaronga i te whakamaroke	<0.50%
Te toenga i runga i te mura	<0.20%
Nga Korewa Taamaha	<20ppm
Te poke kotahi	<0.50%
Nga poke katoa	<1.00%
Wairewa toenga
Pyridine	<4000ppm
Chloroform	<4000ppm
DMF	<3000ppm
Te Maama / Tikanga Tatauria	>99.0%
Tikanga Whakamatau / Tatau	98.5%~101.0% (Kua Tatauhia i runga i te Waiwai)
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	API

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku

Painga:

FAQ:

Taupānga:

Ko te Erlotinib Hydrochloride (CAS: 183319-69-9) he ngota ngota iti o te epidermal growth factor receptor tyrosine kinase reversible inhibitor, te nuinga whakamahia i roto i te maimoatanga o te rohe matatau metastatic ranei mate pukupuku pūtau kore iti pūkahukahu me te raina tuarua ranei e toru raina maimoatanga o mate pukupuku pancreatic.I whakamanahia a Erlotinib Hydrochloride i te marama o Noema, 2004, mo te maimoatanga o te mate pukupuku o te huhu kore-iti-iti ranei.No te karaehe rite ki a Gefitinib, tetahi atu quinazoline i whakaaetia mo te maimoatanga o te mate pukupuku o te huhu o mua, engari he pai ake nga taonga pharmacokinetic.I ahu mai te ngota ngota e Pfizer me te whanaketanga i timatahia i runga i te mahi tahi me OSI, i mau i nga mana katoa ki te tarukino i te hanumi a Pfizer me Warner Lambert.I muri mai, ka uru a Genentech/Roche ki te whakaaetanga raihana me OSI ki te whakawhanake me te hokohoko i te tarukino ki te US me te Ao.Ko te kaiwhakawhiwhi tauwehe epidermal growth factor (EGFR)-tyrosine kinase inhibitor.Atineoplastic.Ko Erlotinib Hydrochloride he aukati HER1 / EGFR me te IC50 o te 2 nM.Kei te waatea a Erlotinib HCl hei 25-, 100-, me te 150-mg papa mo te whakahaere waha.