Fingolimod Hydrochloride CAS 162359-56-0 Purity ≥99.0% (HPLC) API Factory High Purity
Kaihanga me te Pure Nui me te Kounga Pumau
Ingoa matū: Fingolimod Hydrochloride
CAS: 162359-56-0
Ko te Fingolimod Hydrochloride he rongoa kua whakaaetia e te FDA mo te maimoatanga Sclerosis Maha.
API Kounga Teitei, Hanganga Tauhokohoko
Ingoa matū | Finolimod Hydrochloride |
Nga kupu taurite | Fingolimod HCl;FTY 720 |
Tau CAS | 162359-56-0 |
Tau CAT | RF-API39 |
Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
Tātai rāpoi | C19H34ClNO2 |
Taumaha rāpoi | 343.93 |
Iwi Whakarewa | 102.0~107.0°C |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura-White |
Tautuhinga | HPLC |
Iwi Whakarewa | 102.0~106.0 ℃ |
Wairewa | Tino Wairewa ki te wai |
Te Maama / Tikanga Tatauria | ≥99.0% (HPLC) |
makuku (KF) | ≤0.50% |
Te toenga i runga i te mura | ≤0.20% |
Nga Korewa Taamaha | ≤20ppm |
Wairewa toenga | |
Dichloromethane | ≤0.05% |
Ethyl Acetate | ≤0.50% |
Ewaro | ≤0.50% |
Mewaro | ≤0.30% |
Toluene | ≤0.089% |
THF | ≤0.50% |
DMF | ≤0.088% |
Matū Whanaungatanga | |
Te poke kotahi | ≤0.50% |
Nga poke katoa | ≤1.0% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Mahinga Rongoa Hohe (API) |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o Fingolimod Hydrochloride (CAS: 162359-56-0) me te kounga teitei.
Ko te Fingolimod Hydrochloride te rongoa waha tuatahi mo te maimoatanga o te sclerosis maha.He angitu te whakawhanake e te kamupene rongoa Novartis, a kua whakaaetia mo te hokohoko e te US Food and Drug Administration (FDA).Ko te sclerosis maha he mate neurological whakararuraru e taea ai e te manawanui te ngaro te taurite, ka puta nga uaua me etahi atu raruraru nekehanga.Ko te Fingolimod Hydrochloride he kaiwhakaora kaikawe sphingosine-l-phosphate (S1PR).I muri i te phosphorylation, Ka herea ki te s1P receptor kei runga i te mata o te lymphocyte, ka huri i te heke o te lymphocyte, me te whakatairanga i nga pūtau ki roto i te kiko lymphatic, me te aukati i nga lymphocytes mai i te wehe i te kiko lymphoid ka uru ki roto i te raima.Ma reira, ka aukati i enei pūtau ki te kuhu ki te punaha o te puku (CNS), e tutuki ai te painga o te aukati mate.