Fmoc-Leu-OH CAS 35661-60-0 N-Fmoc-L-Leucine Purity >99.0% (HPLC) wheketere
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua o N-Fmoc-L-Leucine (Fmoc-Leu-OH) (CAS: 35661-60-0) me te kounga teitei.Ko Ruifu Chemical he raupapa waikawa amino.Ka taea e taatau te tuku tuku i te ao, te utu whakataetae, te iti me te rahinga e waatea ana.Hoko Fmoc-Leu-OH,Please e-mail: alvin@ruifuchem.com
| Ingoa matū | N-Fmoc-L-Leucine |
| Nga kupu taurite | Fmoc-Leu-OH;Fmoc-L-Leu-OH;Fmoc-L-Leucine;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-Leucine;N-(9-Fluorenylmethoxycarbonyl)-L-Leucine |
| Tūnga Taonga | I roto i te Raarangi, Te Raahanga Whakaputa ki Toni ia Marama |
| Tau CAS | 35661-60-0 |
| Tātai rāpoi | C21H23NO4 |
| Taumaha rāpoi | 353.42 g/mol |
| Iwi Whakarewa | 153.0 ki te 160.0 ℃ |
| Kiato | 1.207±0.06 g/cm3 |
| Tairongo | Hygroscopic |
| Wairewa i te Mewaro | Tata Puataata |
| Rokiroki Temp. | Wahi Matao me te maroke (2~8℃) |
| COA & MSDS | Kei te waatea |
| Kāwai | Waikawa Fmoc-Amino |
| Waitohu | Ruifu Chemical |
| Nga taonga | Nga Paerewa Tirotiro | Hua |
| Te ahua | Paura ma | Paura ma |
| Hurihuri Tau [α]20/D | -25.0°±2.0° (C=1 i DMF) | -24.6° |
| Iwi Whakarewa | 153.0 ki te 160.0 ℃ | 155.1℃ |
| TLC | ≥98.0% | >98.0% |
| Maamaa Optical | <0.30% D-Enantiomer | Ka tutuki |
| Maramatanga o te Otinga | 0.3 karamu i roto i te 2ml DMF Clear Solution | Ka tutuki |
| Kaiser Test | <0.05% | <0.05% |
| Wai na Karl Fischer | <0.50% | 0.12% |
| Ngaronga i te whakamaroke | <0.50% (60℃, 2h) | 0.15% |
| Fmoc-β-Ala-OH | <0.20% (HPLC) | Ka tutuki |
| Fmoc-β-Ala-Leu-OH | <0.10% (HPLC) | Ka tutuki |
| Fmoc-Leu-Leu-OH | <0.10% (HPLC) | Ka tutuki |
| Fmoc-Ile-OH | <0.10% (HPLC) | Ka tutuki |
| Waikawa Amino Kore Utu | <0.20% (GC) | Ka tutuki |
| Ethyl Acetate | <0.50% (GC) | Ka tutuki |
| Te Maama / Tikanga Tatauria | >99.0% (HPLC) | 99.85% |
| Hiranga Papatipu | E ai ki te Paerewa | Ka tutuki |
| NMR Spectrum | E ai ki te Paerewa | Ka tutuki |
| Whakamutunga | Kua whakamatauria te hua me te whai ki nga whakaritenga | |
Mōkī: Pounamu Fluorinated, Peeke pepa konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Rokiroki i roto i nga ipu hiri ki te whare putunga makariri me te maroke (2~8 ℃) i tawhiti atu i nga matū hotokore.Tiaki i te marama me te makuku.
Te tikanga tirotiro
1. Te ahua
-- Te tirotiro tirohanga
2. Pure (HPLC)
2.1 Taputapu
Ko te chromatography wai mahi teitei, te kaitirotiro PDA.
Taurite tātari hiko
2.2 Reagent
Acetonitrile (koeke chromatographic), waikawa Trifluoroacetic (koeke chromatographic)
2.3 Nga tikanga Chromatographic
2.3.1 Tīwae: YMC-ODS-AM, 5μL, 250x4.6 mm
2.3.2 Te roangaru rapu: INC220nm
Rere rere: 1.0mL/min
Rahi tauira: 10μL (tohutohu)
Whakarewa: acetonitrile
Te wa kohikohi raraunga: 25.00min
2.4 Whakaritenga wahanga pūkoro
Waahanga pūkoro A (0.1% te wai waikawa trifluoroacetic): ka uru tika ki te 2.0ml te waikawa trifluoroacetic, te waimeha ki te wai ki te 2000ml, uru pai, me te whakaheke;
Waahanga pūkoro B (0.1% acetonitrile trifluoroacetic acid): te tango tika i te 2.0ml waikawa trifluoroacetic, kua diluted ki te 2000ml me te acetonitrile, te ranu me te whakaheke;
Wā (min) A% B%
0.00 90 10
13.00 10 90
18.00 10 90
18.01 90 10
23.00 90 10
2.6 Te whakarite tauira otinga
Paunatia me te whakakore i te tauira 0.1g me te acetonitrile ka waimeha ki te 100ml, ruru pai hei whakamahi, kia rite ranei te kukū.Whakaritea kia rua nga tauira hei whakarara.
2.7 Tauira Whakatau
Tātarihia te tauira kia rite ki te tikanga tauira e whai ake nei:
Neke atu i te 1 werohanga o te otinga patea
1 wairewa tauira ngira 1#
1 wairewa tauira ngira 2#
2.8 Te Tatau Hua
2.8.1 I whakamahia te tikanga whakatikatika rohe tihi ki te tatau i te pokekore o te HPLC ma te tango i te waahi tuwhera.
2.8.2 Kaua e nui ake i te 1%.
2.8.3 Mena ka tutuki nga hua o nga werohanga e rua ki nga paearu whakaae, ka riro te maatanga toharite hei hua whakamutunga.
3, Ira whakarewa -- RY-1 taputapu ira whakarewa
4. Ngaronga i runga i te whakamaroke tikanga whakamatautau
4.1 Taputapu:
Umu whakamaroke thermostatic hiko, 1/10,000 toenga.
4.2 Tikanga:
I roto i te pounamu pauna he rite tonu te taumaha me te whakamaroke o te waha o te waha o te whenua, paunatia te 1 karamu (tika ki te 0.0001 karamu) o te tauira.Ko te tauira me horahia ki raro o te pounamu pauna me te matotoru kaua e neke atu i te 10mm, ka maka ki roto i te oumu whakamaroke hiko thermostatic, whakamaroke i te 105 ~ 110 ℃ mo te 3 haora, ka neke ki roto i te ruma whakamaroke ki te whakamatao te pāmahana rūma mo te pauna.
Tātaitanga: Ngaronga i te whakamaroketanga %= (M1-M2) ÷M×100
Kei hea: M1: te taumaha o te tauira me te pounamu ine i mua i te whakamaroke, karamu
M2: te taumaha o te tauira me te pounamu ine i muri i te whakamaroketanga, ki te karamu
M: Tauira taumaha, karamu
5. Te hurihanga motuhake
-- Ka inehia te hurihanga motuhake i runga i te GB/T613-1988
Te whakarite tauira: 0.5000g tauira i paunatia tika, ka nekehia ki te pounamu volumetric 50ml ma, maroke, 20ml DMF i tapirihia, ka kapi te pounamu ka ruia kia memeha, katahi ka diluted ki te tauine ki te DMF.
Whakamātautau: Whakaritea te kore o te gyroscope i mua i te whakamatautau, ka utaina te ipuipu whakamatautau me te otinga tauira, tuhia te Koki hurihuri, ka tatau i te hurihanga motuhake o te tauira me te tauira e whai ake nei.
[а]D20=(r×50) ÷ (L×W)
[a]D20: Te hurihanga whatu motuhake i te 25 ℃ o te otinga tauira
r: Ka kitea te hurihanga mata i te 20 ℃ mo te otinga tauira
50: Rōrahi o te otinga tauira kua rite (ml)
w: Tauira taumaha (g)
L: Roa ngongo hurihuri whatu (dm)
Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 tau te wheako?Neke atu i te 15 tau o matou wheako ki te hanga me te kaweake i te whānuitanga o nga momo takawaenga rongoa kounga teitei, matū pai ranei.
Nga maakete matua?Hokona ki te maakete kaainga, Amerika Te Tai Tokerau, Uropi, Inia, Korea, Hapani, Ahitereiria, aha atu.
Nga painga?Ko te kounga teitei, te utu utu, nga ratonga ngaio me te tautoko hangarau, te tuku tere.
KoungaWhakapumautanga?Pūnaha whakahaere kounga tino.Ko nga taputapu ngaio mo te tātari ko te NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Tauira?Ko te nuinga o nga hua e whakarato ana i nga tauira kore utu mo te aromatawai kounga, me utu nga utu kaipuke e nga kaihoko.
Te arotake a wheketere?Nau mai te arotake wheketere.Whakaritea he hui i mua.
MOQ?Kaore he MOQ.Ka whakaaetia te ota iti.
Wā Tukunga? Mena kei roto i nga taonga, e toru nga ra ka whakamanahia te tuku.
Te kawe waka?Ma te Express (FedEx, DHL), ma te Air, ma te Moana.
Tuhinga?I muri i te ratonga hokohoko: COA, MOA, ROS, MSDS, me etahi atu ka taea te whakarato.
Whakaritenga Whakaritenga?Ka taea te whakarato ratonga whakahiato ritenga kia pai ai to hiahia rangahau.
Nga tikanga utu?Ko te nama Proforma ka tukuna tuatahi i muri i te whakapumautanga o te ota, ka kohia o maatau korero peeke.Te utu ma te T/T (Telex Transfer), PayPal, Western Union, etc.
Nga Tohu Moorearea Xi - Irirangi
Waehere Whakararuraru 36/37/38 - He whakapataritari ki nga kanohi, te punaha manawa me te kiri.
Whakaahuatanga Haumaru S22 - Kaua e pupuhi puehu.
S24/25 - Kaua e pa ki te kiri me nga kanohi.
S36/37/39 - Mau kakahu whakamarumaru tika, karapu me te whakamarumaru kanohi/kanohi.
S27 - Wewetehia nga kakahu poke katoa.
S26 - Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora.
WGK Tiamana 3
Waehere HS 2922491990
Ko te N-Fmoc-L-Leucine (Fmoc-Leu-OH) (CAS: 35661-60-0) he pärönaki waikawa amino ka taea te whakarite e te tauhohenga o L-Leucine me 9-Fluorenomethoxycarbonyl Chloride.
Fmoc-amino acids, whakamahia i roto i te peptide synthesis, whakamahia hei takawaenga whakahiato waro, takawaenga rongoa, reagent biochemical, reagent matū ranei.
Fmoc-L-Leu-OH, he waikawa amino pärönaki, whakamahia i roto i te matū peptide.Paraka hanga paerewa mo te whakahiato peptide wahanga totoka e whai ana i nga tikanga Fmoc.Ko tetahi o nga pukapuka PPARγ ligands ka taea te whakahohe i te PPARγ i roto i nga huarahi rereke, e whakaiti ana i te rereketanga o nga osteoclasts, na reira he pai ake nga whaainga rongoa mo te mate huka atu i nga raau taero antidiabetic tuku iho.
Te Whakaritenga 1.05g (0.008 mol) L-Leucine totoka ka rewa ki te 10% konutai warowaiwai wairewa, ka whakaohokia kia tino rewa te glycine totoka, me te 9-fluorene methoxycarbonyl chloride (2.10g, 0.008 mol) wairewa rewa i roto i te toluene (205) ml2~ ka tapirihia te maturuturunga iho ki te 20~30 ℃, whakahekehia te taapiri mo te 30 ~ 60 meneti, ka mutu te taapiri whakaheke, whakaoho i te 20 ~ 30 ℃ mo te 1 ~ 8 haora, taapirihia te 30-200 ml o te wai ki te waimeha, ka tango ki te n-butyl acetate (80 ml) ki te tango i te taikaha 9-fluorene methoxycarbonyl chloride, Ko te wahanga wai kua whiwhi ka waikawa ki te waikawa puota ki te PH = 0.5~3.5, ka tangohia ki te n-butyl acetate (80 ml), a ko te wahanga hinu kua riro ko. ka horoia ki te wai hei tango i te waikawa maatawai, ko te wahanga o te hinu ki te tango i te wairewa n-butyl acetate, ko nga kiripiri ma ka whakahekehia, ka taraihia ka whakamaroke kia whiwhi 2.46g o Nα-9-fluorene methoxycarbonyl-L-leucine, me te hua o te 87.0 %.
-
L-Arginine Hydrochloride CAS 1119-34-2 (H-Arg-O...
-
BOP-Cl CAS 68641-49-6 Reagent Hononga Peptide ...
-
Boc-L-Norvaline DCHA CAS 67861-96-5 Assay >98.0...
-
S-Methyl-L-Cysteine CAS 1187-84-4 H-Cys(Me)-OH ...
-
O-Benzyl-L-Serinol Hydrochloride CAS 58577-87-0...
-
BOP Reagent CAS 56602-33-6 Rea Whakahono Peptide...