Gemcitabine CAS 95058-81-4 Assay 98.0~102.0%
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua o Gemcitabine (CAS: 95058-81-4) me te kounga teitei.Ka taea e Ruifu Chemical te tuku i te ao, te utu whakataetae, te ratonga pai, te iti me te rahinga e waatea ana.Hokona Gemcitabine,Please contact: alvin@ruifuchem.com
| Ingoa matū | Gemcitabine |
| Nga kupu taurite | 2'-Deoxy-2', 2'-Difluorocytidine;4-Amino-1-[3,3-Difluoro-4-Hydroxy-5-(Hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;dFDC;Gemzar (Lilly);LY-188011;dFdCyd;DDFC;2',2'-Difluoro-2'-deoxycytidine;2',2'-Difluorodeoxycytidine;Folfugem;Kīwaha kōhatu;Gemcel;Gamcitabine |
| Tūnga Taonga | I roto i te Stock, Production Raukaha 5 Tons |
| Tau CAS | 95058-81-4 |
| CAS e pa ana | 122111-03-9 |
| Tātai rāpoi | C9H11F2N3O4 |
| Taumaha rāpoi | 263.20 g/mol |
| Iwi Whakarewa | 217.0 ki te 222.0 ℃ |
| Kiato | 1.84±0.10 g/cm3 |
| Tairongo | Te werawera |
| Wairewa wai | Kare e memeha ki te wai |
| COA & MSDS | Kei te waatea |
| Taketake | Shanghai, Haina |
| Waitohu | Ruifu Chemical |
| Nga taonga | Whakatakotoranga | Hua |
| Te ahua | Paura ma, tata ranei ma te kirikiriata, kaore he kakara | Ka tutuki |
| Cytosine | ≤0.10% | 0.002% |
| α-Isomer | ≤0.10% | 0.01% |
| Te poke takitahi | ≤0.10% | 0.03% |
| Nga poke katoa | ≤1.00% | 0.10% |
| Wai na Karl Fischer | ≤1.00% | 0.67% |
| Hurihuri Tauwhāiti | +68.0°~+74.0° | +70.5° |
| Nga Korewa Taamaha | ≤10ppm | <10ppm |
| Te toenga i runga i te mura | ≤0.10% | 0.03% |
| Whakamātautau (Na HPLC) | 98.0%~102.0% | 99.9% |
| Spectrum Infrared | E rite ana ki te Hanganga | Ka tutuki |
| 1H NMR Spectrum | E rite ana ki te Hanganga | Ka tutuki |
| Whakamutunga | Kua whakamatauria te hua me te whai ki nga whakaritenga kua tohua | |
Mōkī:Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Kia kati tonu te ipu ka penapena ki roto i te whare putunga hauhautanga, maroke me te hau pai kia matara atu i nga matū hotokore.A ape i te pa ki te ra tika, te makuku me te wera nui.
Tukunga:Tukuna ki te ao ma te rangi, ma te FedEx / DHL Express.Whakaratohia te tuku tere me te pono.
Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 tau te wheako?Neke atu i te 15 tau o matou wheako ki te hanga me te kaweake i te whānuitanga o nga momo takawaenga rongoa kounga teitei, matū pai ranei.
Nga maakete matua?Hokona ki te maakete kaainga, Amerika Te Tai Tokerau, Uropi, Inia, Korea, Hapani, Ahitereiria, aha atu.
Nga painga?Ko te kounga teitei, te utu utu, nga ratonga ngaio me te tautoko hangarau, te tuku tere.
KoungaWhakapumautanga?Pūnaha whakahaere kounga tino.Ko nga taputapu ngaio mo te tātari ko te NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Tauira?Ko te nuinga o nga hua e whakarato ana i nga tauira kore utu mo te aromatawai kounga, me utu nga utu kaipuke e nga kaihoko.
Te arotake a wheketere?Nau mai te arotake wheketere.Whakaritea he hui i mua.
MOQ?Kaore he MOQ.Ka whakaaetia te ota iti.
Wā Tukunga? Mena kei roto i nga taonga, e toru nga ra ka whakamanahia te tuku.
Te kawe waka?Ma te Express (FedEx, DHL), ma te Air, ma te Moana.
Tuhinga?I muri i te ratonga hokohoko: COA, MOA, ROS, MSDS, me etahi atu ka taea te whakarato.
Whakaritenga Whakaritenga?Ka taea te whakarato ratonga whakahiato ritenga kia pai ai to hiahia rangahau.
Nga tikanga utu?Ko te nama Proforma ka tukuna tuatahi i muri i te whakapumautanga o te ota, ka kohia o maatau korero peeke.Te utu ma te T/T (Telex Transfer), PayPal, Western Union, etc.
Waehere Morearea R21 - He kino ki te pa ki te kiri
R36/38 - He whakapouri ki nga kanohi me te kiri.
R46 - Ka kino pea te ira
R62 - Ka tupono pea ka paheke te hua
R63 - Ka tupono pea he kino ki te tamaiti kare i whanau
Whakaahuatanga Haumaru S25 - Kaua e pa ki nga kanohi.
S26 - Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora.
S36/37 - Mau kakahu whakamarumaru me nga karapu tika.
S53 - A ape i te rongo - whiwhi tohutohu motuhake i mua i te whakamahi.
Waehere HS 2934999091
Paitini LD10 iv i te kiore: 200 mg/m2 (Abbruzzese)
Ko te Gemcitabine (CAS: 95058-81-4) he rongoa haumanu e whakamahia ana hei rongoa i etahi momo mate pukupuku.Kei roto i tenei ko te mate pukupuku o te u, te mate pukupuku pūtau kore-iti, te mate pukupuku pancreatic, te pukupuku pukupuku, me te mate pukupuku o te waahanga biliary.Kei te tirotirohia te Gemcitabine mo te whakamahi ki te mate pukupuku esophageal, ka whakamahia hei whakamatautau i nga lymphomas me etahi atu momo pukupuku.Ko te Gemcitabine e whakahaeretia ana ma te ara intravenous, na te mea ka kaha te whakahiato e te gastrointestinal tract.
Ko te Gemcitabine he analogue nucleotide, no te karaehe anti-metabolic o nga raau taero anticancer.Ko te nuinga o te mahi i runga i te wahanga whakahiato DNA, ara, te wahanga S.I raro i etahi tikanga, ka taea e ia te aukati i te wahanga G1 mai i te ahu whakamua ki te wahanga S.Kei a ia nga ahuatanga o te whanui anticancer spectrum, te tikanga ahurei o te mahi, te iti o te paitini, kaore he whiti-whakawhitinga ki etahi atu raau taero chemotherapy me te kore o te tuunga o te paitini.Ko te Chemicalbook, gemcitabine, kua whakaaetia inaianei mo te whakamahi i roto i te neke atu i te 90 whenua, na reira ko te rongoa tuatahi mo te mate pukupuku o te puku kore-iti me te "paerewa koura" mo te mate pukupuku pancreatic.
I te tau 1999, i whakaaetia e te CFDA te gemcitabine mo te maimoatanga o te NSCLC matatau o te rohe, te metastatic ranei, te mate pukupuku pancreatic mate pukupuku o te rohe, te metastatic ranei;I te tau 2010, ka whakaaetia e CChemicalbookFDA te gemcitabine me te paclitaxel mo te maimoatanga o te mate pukupuku o te u e kore e taea te whakakore, te mate pukupuku o te rohe, te mate pukupuku metastatic ranei kua hoki mai i muri i te adjuvant / neoadjuvant chemotherapy.
Ko te Gemcitabine he antimetabolite whanui me te deoxycytidine analogue me te mahi antineoplastic.I runga i te whakahaerenga, ka hurihia te gemcitabine ki nga metabolites kaha difluorodeoxycytidine diphosphate (dFdCDP) me te difluorodeoxycytidine triphosphate (dFdCTP) na te deoxycytidine kinase.Ka whakataetae te dFdCTP me te deoxycytidine triphosphate (dCTP) ka whakauruhia ki roto i te DNA.Ma tenei ka maukati te polymerase DNA na reira ka mutu te huna huna i te wa e tukurua ana te DNA.I tetahi atu taha, ka aukati te dFdCDP i te ribonucleotide reductase, na reira ka whakaheke i te puna deoxynucleotide e waatea ana mo te whakahiato DNA.Ko te whakaheke i te kukū intracellular o te dCTP ka kaha te whakauru o te dFdCTP ki te DNA.
