Glimepiride CAS 93479-97-1 Assay 98.0%~102.0% API Factory High Pure
Whakarato me te Maama me te Kounga Pumau
Ingoa matū: Glimepiride
CAS: 93479-97-1
Glimepiride i roto i te maimoatanga o te Noninsulin-Dependent Type 2 Diabetes Mellitus
API Kounga Teitei, Hanganga Tauhokohoko
Ingoa matū | Glimepiride |
Nga kupu taurite | Amaryl |
Tau CAS | 93479-97-1 |
Tau CAT | RF-API24 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C24H34N4O5S |
Taumaha rāpoi | 490.62 |
Iwi Whakarewa | 212.2~214.5℃ |
Tikanga Tukunga | I raro i te Paemahana Ambient |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paura ma, tata ma ranei |
Tautuhinga | IR (He rite ki te Paerewa) |
Nga Taonga Paanga | |
Cis-Isomer (A) | ≤0.80% |
Sulfonamide (B) | ≤0.40% |
Uretana (C) | ≤0.10% |
3-Isomer (D) | ≤0.20% |
Tetahi atu poke | ≤0.10% |
Nga poke katoa | ≤0.50% |
Ngaronga i te whakamaroke | ≤0.50% |
Te toenga i runga i te mura | ≤0.10% |
Nga Korewa Taamaha | ≤0.001% |
Te whakamatautau | 98.0%~102.0% |
Paerewa Whakamatau | Te Rongoa o te Pakeha (EP);United States Pharmacopoeia (USP) |
Whakamahinga | Mahinga Rongoa Hohe (API) |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o Glimepiride (CAS: 93479-97-1) me te kounga teitei, te whakauru rongoa kaha (API).Ko te Glimepiride he rongoa mo te mate huka e awhina ana ki te whakahaere i nga taumata huka toto.Ko te Glimepiride he sulfonylurea-whakatupuranga tuatoru me te mahi hypoglycemic.
Ko te Glimepiride (te ingoa hokohoko tuatahi ko Amaryl) he rongoa rongoa sulfonylurea-a-waha e waatea ana mo te mate huka.Pērā i ngā sulfonylureas katoa, ko te glimepiride te mahi hei mahi huna mo te insulin.Ka whakahekehia te huka toto ma te whakaihiihi i te tukunga o te insulin mai i nga pūtau beta pancreatic e mahi ana me te whakanui ake i te tairongo o nga kopa peripheral ki te insulin.Ka herea pea a Glimepiride ki nga kaiwhakawhiwhi hongere pāhare pāporo ATP-tairongo i runga i te mata o te pūtau pancreatic, ka whakaheke i te whakahaerenga pāhare pāporo me te whakaheke i te kiriuhi.Ko te whakahekenga o te membrane e whakaihiihi ana i te urunga katote konupūmā i roto i nga awa konupūmā ngaohiko-tairongo.Ko tenei pikinga o te konupūmā konupūmā kukū katote i roto i te pūtau ka whakaawe i te hunanga o te insulin.Ko te Glimepiride te nuinga e whakamahia ana ki te rongoa i nga turoro me te mate huka momo 2 ka taea hoki te whakaiti i te tupono ka pa mai te mate o te mate huka momo 2.I whakaaetia te tarukino e te FDA i te tau 1995 ka hangaia e Sanofi-Aventis.Ka taea te whakamahi i te taha o te kai tika me te kaupapa whakakori tinana, ka taea hoki te whakamahi mo ia anake, me etahi atu rongoa mate huka mena ka hiahiatia.Ka taea te whakamahi i te Glimepiride hei monotherapy me te whakakotahi ranei me te insulin.