Guanfacine Hydrochloride Guanfacine HCl CAS 29110-48-3 API USP Paerewa Pure Teitei
Kaihanga me te Pure Nui me te Kounga Pumau
Ingoa matū: Guanfacine Hydrochloride
Nga kupu taurite: Guanfacine HCl
CAS: 29110-48-3
Ko te Guanfacine Hydrochloride he agonist α2A-adrenoceptor whiriwhiri.Te whakaheke toto
API Kounga Teitei, Hanganga Tauhokohoko
Ingoa matū | Guanfacine Hydrochloride |
Nga kupu taurite | Guanfacine HCl |
Tau CAS | 29110-48-3 |
Tau CAT | RF-API40 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C9H10Cl3N3O |
Taumaha rāpoi | 282.55 |
Iwi Whakarewa | 211.0~215.0 ℃ |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura Tioata-White |
Tautuhinga | Infrared Absorption;HPLC |
Ngaronga i te whakamaroke | ≤0.50% |
Te toenga i runga i te mura | ≤0.10% |
Nga Korewa Taamaha | ≤20ppm |
Te whakamatautau | 98.0%~102.0% (HPLC i runga i te tikanga maroke) |
Pure Chromatographic | ≥99.0% |
Paerewa Whakamatau | USP Paerewa |
Whakamahinga | Mahinga Rongoa Hohe (API) |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o Guanfacine Hydrochloride (CAS: 29110-48-3) me te kounga teitei.
Ko te Guanfacine hydrochloride e mahi ana i te agonist a-adrenoceptor.Te whakaheke toto.Ko te Guanfacine hydrochloride, he kaihoko anti-hypertensive, he agonist α2A-adrenoceptor whiriwhiri me te Kd o 31 nM me te whakaatu i te 60-fold selectivity i runga i te α2B-adrenoceptors.Ka whakahekehia e Guanfacine te pehanga toto systolic me te diastolic na roto i te whakahohe i te punaha nerve matua α2A norepinephrine autoreceptors, e hua ai te heke o te rerenga aroha o te peripheral me te whakaiti i te tangi o te aroha.Ko nga tono rongoa mo te guanfacine he rite ki era o era atu agonists α2-adrenergic me te methyldopa.Kua whai hua hei monotherapy i roto i te maimoatanga o nga turoro he ngawari ki te whakaheke toto.