H-Gly-OMe·HCl CAS 5680-79-5 Glycine Methyl Ester Hydrochloride Assay >99.0%

1. Āhuatanga: Ko tenei hua kia ma te paura tioata.
2. Whakatau:
1) Te whakatau i te Glycine Methyl Ester Hydrochloride assay
1.1 Tikanga
I raro i nga tikanga waikawa, ka tauhohe te tauira ki te nui o te pakawa hiriwa, a ko te taikaha hiriwa ka whakahoki ano ki te ammonium thiocyanate, e tohu ana ki te ammonium ferric sulfate.
Hei tohu, i whakatauhia te tapeke o te maaota i runga i te nui o te wairewa paerewa i pau, a ka tangohia te katoa o te maaota i roto i te ihirangi o te glycine hydrochloride ki te whiwhi i te ihirangi Glycine Methyl Ester Hydrochloride.
1.2 Reagents
Dibutyl phthalate;
Waihanga waikawa Nitric: 2+3;
Te wairewa inenga paerewa pakawa hiriwa: c(AgNO3) = 0.1 mol/L
Te haukinia thiocyanate wairewa titration paerewa: c(NH4SCN) = 0.1 mol/L
Te wai tohu haukinia ferric sulfate (III): 80 g/L
1.3 Tikanga tātari
Kia 0.5g tauira te pauna, tika ki te 0.0001g.Whakanohoia ki roto i te ipu koeko 250ml, memeha ki te 40ml wai, tāpirihia te 10 ml wairewa waikawa nitric, Tāpiri (50 ± 0.02) mL wairewa pākawa hiriwa titration wairewa, 3mL haukinia ferric sulfate wairewa tohu, 4mL dibutyl phthalate, me te thiocyanate Ko te wairewa paerewa haukinia. titrated tae noa ki te marama parauri te otinga ka noho kore tae mo te 30 hēkona.
1.4 Te tatauranga hua
Ko te hautau papatipu o te glycine methyl ester hydrochloric acid content w1, e whakaatuhia ana hei %, ka tatauhia i runga i te Wharite (1):
w1= (c1V1-c2V2)*M/1000/m * 100-w2 *1.126 tātai (1)
Kei hea:
V1: Rōrahi o te wairewa wairewa inenga paerewa pākawa (ml)
V2: Rōrahi o te haukinia thiocyanate wairewa whakamaoritanga paerewa i pau i te ine (ml)
c1: Te uara totika o te wairewa wairewa inenga paerewa pakawa (mol/L)
c2: Te uara tika o te wairewa whakamaoritanga paerewa haukinia thiocyanate (mol/L)
w2: Ko te hautanga papatipu (%) o te ihirangi glycine hydrochloride i whakatauhia i te Wahanga 4.2
M: Papatipu molar o te glycine methyl ester hydrochloride (g/mol)
1.126: Te whakarea huringa o te glycine hydrochloride ki te Glycine methyl ester hydrochloride.
Ko te uara tikanga tatau o nga hua ine whakarara e rua i tangohia hei hua ine, a, ko te tino rereketanga i waenga i nga hua ine whakarara e rua kaua e neke ake i te 0.05%.
2) Te whakatau i te ihirangi glycine hydrochloride
2.1 Tikanga
Ma te whakamahi i te dimethyl kowhai hei tohu, ka tohua te tauira ki te wairewa konutai konutai, ka tohua te rōrahi o te otinga kia rite ki te kai o te paerewa konutai waikawa.
Tātaihia te ihirangi glycine hydrochloride.
2.2 Reagent
Wairewa inenga paerewa o te konutai waihā: c (NaOH) = 0.1mol/L
Te wai tohu kowhai Dimethyl: 10 g/L
2.3 Te Tikanga Tätari
Paunatia te 5.0 g tauira taiwhanga, tika ki te 0.0001g, ki roto i te ipurau 200 ml, memeha ki te 50ml wai, ka tapiri kia 5 nga pata o te dimethyl.
Ko te wai tohu tohu kowhai, me te konutai waikawa te wairewa wairewa titration titration tae noa ki te otinga mai i te whero ki te karaka kowhai ko te pito mutunga
2.4 Te Tatau Hua
Ko te hautau papatipu w2 o te ihirangi glycine hydrochloride ka whakaatuhia hei% ka tatauhia i runga i te Wharite (2):
w2 =(V/1000)cM/m *100 tātai (2)
Kei hea:
V: Rōrahi o te konutai waihā wairewa inenga paerewa (mL)
c: Te uara tika o te konutai waikawa te kukū wairewa inenga paerewa (mol/L)
M: Papatipu molar o te glycine hydrochloride (g/mol)
m: Uara papatipu o te tauira (g)
Ko te uara tikanga tatau o nga hua inenga whakarara e rua i tangohia hei hua ine, a ko te tino rereketanga i waenga i nga hua ine whakarara e rua kaua e neke ake i te 0.05%
3. Ira whakarewa: E ai ki te tikanga mo te whakatau i te waahi whakarewa (Hainamana Pharmacopoeia 2010 Appendix VIC), ko te awhe rewa ko te 172-178 ºC.
4. Te whakamaroke i te mate taimaha: tangohia tenei hua ki te 105.0 ℃ ka whakamaroke ki te taumaha tonu.Ko te mate taimaha kaua e neke ake i te 0.5%.
5. Rokiroki: Me whakamatao tenei hua mai i te marama.