Ibrutinib Deacryloylpiperidine CAS 330786-24-8 Purity >99.0% (HPLC)
Ingoa matū | 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Nga kupu taurite | Ibrutinib intermeidate N-2;Ibrutinib Deacryloylpiperidine;Ibrutinib poke 8;5-(4-Phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine;IBT4A;Ibrutinib N-Despiperidinyl poke |
Tau CAS | 330786-24-8 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C17H13N5O |
Taumaha rāpoi | 303.32 |
Te Whakarewa | >262℃(tikuri) |
Kiato | 1.380±0.06 g/cm3 |
Te akomanga morearea | 6.1;paihana |
Roopu Tarapi | III |
COA & MSDS | Kei te waatea |
Taketake | Shanghai, Haina |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Pau-White ki te Paura Khaki |
Tautuhinga | HNMR, LC-MS |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
Ngaronga i te whakamaroke | <1.00% |
Takitahi Max.poke | <1.00% |
Nga poke katoa | <1.00% |
Konga Taamaha (hei Pb) | <20ppm |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Ibrutinib (CAS: 936563-96-1) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.
3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS: 330786-24-8) he takawaenga waihanga whai hua i roto i te whakahiato o Ibrutinib (CAS: 936563-96-1 ).Ko te Ibrutinib he momo aukati Bruton tyrosine kinase (BTK), ka taea te whakamahi mo te maimoatanga o te mate pukupuku lymphocytic tawhito (CLL) me te lymphoma pūtau koroka (MCL).Ko te MCL me te CLL no te lymphoma kore-Hodgkin B-cell, he uaua ki te rongoa me te ngawari ki te hoki mai.Ko te whakamaarama matū matū noa kaore he whaainga, he maha nga wa e 3, e 4 nga tauhohenga kino.Ka taea e nga lymphocytes Ibrutinib me B te whai ki te BTK e tika ana mo te hanga, te rereketanga, me te tuku korero, te aukati i te mahi BTK e kore e taea te huri, me te aukati i te tipu o nga pūtau puku me te ora.Ka taea e Ibrutinib te tere tere i muri i te whakahaere a-waha, i roto i te 1 ~ 2h ka tae ki te nui o te toto toto, ko nga tauhohenga kino no te kotahi, e rua ranei, na reira, ka waiho a Ibrutinib hei whiringa hou mo te maimoatanga o CLL me MCL.