N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Pure

Whakaahuatanga Poto:

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pirimidin-2-amine

CAS: 152460-09-8

Te ahua: Kowhai, Tata ranei te Paura Kowhai

Maamaa: ≥98.0% (HPLC)

Takawaenga o Imatinib Mesylate (CAS: 220127-57-1) i te maimoatanga o Philadelphia Chromosome-Positive Chronic Myeloid Leukemia (Ph+CML)

Kounga Teitei, Hanganga Tauhokohoko

Inquiry: alvin@ruifuchem.com


Taipitopito Hua

Hua e Pa ana

Tohu Hua

Whakaahuatanga:

Nga Ahuatanga matū:

Ingoa matū N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pirimidin-2-amine
Nga kupu taurite Imatinib Mesylate Intermediate;2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pirimidine
Tau CAS 152460-09-8
Tau CAT RF-PI228
Tūnga Taonga I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi C16H13N5O2
Taumaha rāpoi 307.31
Te Whakarewa 188.0~193.0℃
Waitohu Ruifu Chemical

Whakatakotoranga:

Tūemi Whakatakotoranga
Te ahua Paura Kōwhai, Tata Kowhai ranei
Maamaa ≥98.0% (HPLC)
makuku (KF) ≤0.50%
Nga poke katoa ≤2.0%
Mōrahi Kore kotahi ≤1.0%
Te toenga i runga i te mura ≤0.50%
Nga Korewa Taamaha ≤20ppm
Paerewa Whakamatau Paerewa hinonga
Whakamahinga Takawaenga o Imatinib Mesylate (CAS: 220127-57-1)

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.

Painga:

1

FAQ:

Taupānga:

Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o N-(2-Methyl-5-nitrophenyl) -4-(pyridin-3-yl)pyrimidin-2-amine (CAS: 152460-09-8) me te kounga teitei.He takawaenga i te nuinga o te wa i te whakahiatotanga o Imatinib Mesylate (CAS: 220127-57-1).
Ko te Imatinib Mesylate he ngota ngota iti e aukati ana i te c-Abl protein-tyrosine kinase, He mea tino motuhake mo te BCR-ABL, te enzyme e pa ana ki te reukemia myelogenous ma'i (CML) me etahi momo o te mate lymphoblastic leukemia (KATOA).He takahanga whakawhiti i waenga i nga chromosomes 9 me te 22 ka whakaputa i te chromosome Philadelphia, katahi ka whakaputa i te pūmua whakakotahi Bcr-Abl me te ngohe kinase aberrant e whakatairanga ana i te tipu tere o te pūtau.Ka herea e Imatinib Mesylate tenei kinase whakahirahira, ka aukati i te tipu o te CML.Kua whakaatuhia ano te Imatinib Mesylate ki te aukati i te PDGFR me te tyrosine kinases e hono ana ki te c-Kit.Kua whakamahia nga rongoa kei roto Imatinib Mesylate ki te rongoa i nga momo mate pukupuku.

Tuhia to korero ki konei ka tukuna mai ki a matou