Irbesartan CAS 138402-11-6 Purity >99.0% (HPLC) API Factory Antihypertensive
Kaihanga Kaihanga, Te Maamaa Teitei, Te Hanga Aromoni
| Ingoa matū | Irbesartan |
| Nga kupu taurite | BMS-186295;SR-47436;Aprovel;Avapro;2-Butyl-3-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]kore-1-en- 4-kotahi;2-Butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]kore-1-en-4-one |
| Tau CAS | 138402-11-6 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C25H28N6O |
| Taumaha rāpoi | 428.54 |
| Kiato | 1.30±0.10 g/cm3 |
| Wairewa i te wai | Karekau ki te wai |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahuatanga | Ma ki te Paura Tioata-Ma-Ma, He iti te wairewa ki te waipiro me te methylene chloride, kare e rewa ki te wai |
| Identification Infrared Absorption | Ko te tuāwhiorangi IR e rite ana ki te tuāwhiorangi i whiwhi ki a Irbesartan RS |
| Tautuhinga 2 | Ko te wa pupuri o te tihi nui i roto i te chromatogram o te whakamatautau ka rite ki a Irbesartan RS |
| Te Maama / Tikanga Tatauria | >99.5% (HPLC) |
| Wai | <0.50% |
| Nga Korewa Taamaha | <0.002% |
| Te toenga i runga i te mura | <0.10% |
| Nga Taonga Paanga | (Na HPLC) |
| USP poke A | <0.20% |
| Tetahi poke kore mohiotia | <0.10% |
| Nga poke katoa | <0.50% |
| Ko nga mea pokekore | Ka tutuki nga whakaritenga a USP |
| Te toenga Azide | <10ppm |
| Wairewa toenga | (Na GC) |
| Ewaro | <5000ppm |
| Toluene | <890ppm |
| Dichloromethane | <3000ppm |
| N,N-Dimethylformamide | <880ppm |
| T-Butyl Methyl Ether | <5000ppm |
| Te whakamatautau | 98.0~102.0% (kua tātaihia i runga i te waikore) |
| Paerewa Whakamatau | Paerewa hinonga;USP Paerewa |
| Whakamahinga | API;Antihypertensive;Mo te maimoatanga o te whakaheke toto |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko Irbesartan (CAS: C) he angiotensin II antagonist kaiawhina e whakamahia ana mo te maimoatanga o te whakaheke toto.I whakawhanakehia a Irbesartan e Sanofi Research (inaianei he wahanga o Sanofi-Aventis).Kei te hokohoko tahi e Sanofi-Aventis me Bristol-Myers Squibb i raro i nga ingoa hokohoko Aprovel, Karvea, me Avapro.Ka whakamahia a Irbesartan ki te rongoa i te toto toto tiketike.I whakarewahia a Avapro i Tiamana, te UK me te US mo te whakaheke toto.Ka rite ki nga antagonists katoa o te angiotensin II, ka tohuhia te irbesartan mo te maimoatanga o te whakaheke toto.Ka taea hoki e Irbesartan te whakaroa i te ahunga whakamua o te nephropathy mate huka me te tohu mo te whakaheke i te ahunga whakamua o te mate renal i nga turoro me te mate huka momo 2, te whakaheke toto me te microalbuminuria (> 30 mg / 24 haora) me te proteinuria ranei.Ka taea hoki e Irbesartan te whakaheke i te whakarereketanga hiko o te myocardium, na reira ka whakaiti i te mate o nga turoro me te whakaheke toto, koinei te rongoa tino whai hua mo te maimoatanga o te mate whakaheke toto me te mate cardiovascular.
