Irbesartan Intermediate Side Chain Hydrochloride CAS 151257-01-1 Purity >99.0% (HPLC) Factory
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Ingoa matū | 2-Butyl-1,3-diazaspiro[4.4]kore-1-en-4-one Hydrochloride |
Nga kupu taurite | Irbesartan Side Chain Hydrochloride;Irbesartan Lactam poke;Irbesartan poke A;2-Butyl-4-spirocyclopentane-2-imidazolin-5-one Hydrochloride;2-Butyl-1,3-diaza-spiro[4.4]kore-1-en-4-one HCl |
Tau CAS | 151257-01-1 |
Tau CAT | RF-PI1894 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C11H18N2O·HCl |
Taumaha rāpoi | 230.74 |
Wairewa i te wai | Wairewa ki te wai |
Te Whakarewa | 235.0~240.0℃ |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te paura tioata tata ma |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
Ngaronga i te whakamaroke | <0.50% |
Te toenga i runga i te mura | <0.20% |
Nga poke katoa | <1.00% |
Proton NMR Spectrum | He rite ki te Hanganga |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Irbesartan (CAS: 138402-11-6) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko te 2-Butyl-1,3-diazaspiro[4.4]kore-1-en-4-one Hydrochloride (CAS: 151257-01-1), e mohiotia ana ko Irbesartan Side Chain Hydrochloride, he Takawaenga o Irbesartan (Avapro) (CAS : 138402-11-6).Ko Irbesartan te angiotensin II kaitao kaikawe, ka wehea nga angiotensin II ki te AT1, AT2, ka taea e irbesartan te aukati i te AngⅠte huri hei AngII ma te maataki i te aukati i te kaiawhina AT1 o AngII, ina koa te whakahē i te angiotensin te huri i te enzyme 1 receptor (AT1), ko te antagonism o AT1 he 8500 nga wa atu i tera o AT2, ka taea te aukati i te tukunga o te vasoconstriction me te aldosterone ma te aukati i te AngII herea me te kaiwhakawhiwhi AT1 me te hua ki te paanga antihypertensive.Karekau tenei hua e aukati i te angiotensin converting enzyme (ACE), renin, me etahi atu whakaihiihi taiaki, kare hoki e pehi i te ture pehanga toto me te toenga o nga awa katote konutai.Ka taea hoki e Irbesartan te whakaheke i te whakarereketanga hiko o te myocardium, na reira ka whakaiti i te mate o nga turoro me te whakaheke toto, koinei te rongoa tino whai hua mo te maimoatanga o te mate whakaheke toto me te mate cardiovascular.