Lenvatinib Mesylate Intermediate CAS 15568-85-1 Purity >97.0% (HPLC) Factory
Ruifu Chemical Supply Lenvatinib Mesylate Intermediates With High Pure
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Ingoa matū | 5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione |
Nga kupu taurite | 5-(Methoxymethylene) Te Waikawa Meldrum;Cabozantinib poke 56;Lenvatinib poke 79 |
Tau CAS | 15568-85-1 |
Tau CAT | RF-PI1967 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C8H10O5 |
Taumaha rāpoi | 186.16 |
Te Whakarewa | 132.0~134.0 ℃ |
Kiato | 1.297±0.06 g/cm3 |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paura Kōwhai |
1 H NMR Spectrum | E rite ana ki te Hanganga |
Te Maama / Tikanga Tatauria | >97.0% (HPLC) |
Nga poke katoa | <3.00% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Lenvatinib Mesylate (CAS: 857890-39-2) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
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5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione (CAS:15568-85-1) he takawaenga o Lenvatinib Mesylate (CAS: 857890-39-2).Ko Lenvatinib he rongoa mate pukupuku thyroid i whakawhanakehia e Eisai Corporation o Hapani (Waehere: E7080), no roto i te aukati o te waha maha-receptor tyrosine kinase (RTK) ka taea te aukati i te mahi kinase o te vascular endothelial growth factor (VEGF) Receptors VEGFR1 ( FLT1), VEGFR2 (KDR), me VEGFR3 (FLT4).Ka taea hoki e Lenvatinib te whakakore i te whakauru o etahi atu RTK i roto i te angiogenesis pathological, te tipu o te pukupuku, me te haere o te mate pukupuku engari mo o raatau mahi pūtau noa tae atu ki te fibroblast growth factor (FGF) nga kaiwhiwhi FGFR1, 2, 3, me te 4;te kaikawe tauwehe tipu i ahu mai i te platelet (PDGFR [alpha]), KIT, me te RET.[Nga Tohu]: He pai a Lenvatinib mo te maimoatanga o nga turoro o te mate pukupuku taikaro o te hokinga mai o te rohe, te momo metastasis ranei, te momo ahunga whakamua me te momo rerekee o te iodine-refractory radioactive.I te Hui-tanguru 13, 2015, i whakaaetia e te US FDA te tarukino anticancer Lenvatinib mo te maimoatanga o te mate pukupuku thyroid.Ko te Lenvatinib he aukati maha-whaanui-a-whaanui, he kaha ki te aukati i te VEGFR2 me te VEGFR3 (te kaikawe tauwehe endothelial vascular).Ko te ingoa hokohoko o Lenvatinib ko Lenvima.I te Haratua 20, 2015, i whakaaetia e te European Medicines Agency (EMA) a Lenvatinib mo te maimoatanga o te mate urutomo, te matatau o te rohe, te metastatic rereke ranei (papillary, follicular, Hurthle momo) mate pukupuku thyroid (DTC).I roto i te whakamatautauranga, ko te wa roa mo te oranga mo nga turoro o te DTC radioactive iodine-refractory DTC i tukuna ki a Lenvatinib he 18 marama ko te uara mo nga turoro e tango placebo he 3 marama anake.
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Lenvatinib Mesylate Intermediate CAS 15568-85-1...
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Lenvatinib Mesylate CAS 857890-39-2 Assay 98.0~...
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Desquinolinyl Lenvatinib CAS 796848-79-8 Purity...
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4-Amino-3-Chlorophenol CAS 17609-80-2 Lenvatini...
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4-Amino-3-Chlorophenol Hydrochloride CAS 52671-...
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4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 4...
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Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8...
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Lenvatinib Mesylate Intermediate CAS 205448-65-...
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Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylat...