Lenvatinib Mesylate Intermediate CAS 15568-85-1 Purity >97.0% (HPLC) Factory

Whakaahuatanga Poto:

5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione

CAS: 15568-85-1

Maamaa: >97.0% (HPLC)

Te ahua: Kowhai Paura

Takawaenga o Lenvatinib Mesylate CAS 857890-39-2

Whakapā: Takuta Alvin Huang

Pūkoro/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tukuna he imeera ki a matou

Taipitopito Hua

Hua e Pa ana

Tohu Hua

Whakaahuatanga:

Ruifu Chemical Supply Lenvatinib Mesylate Intermediates With High Pure
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Nga Ahuatanga matū:

Ingoa matū	5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione
Nga kupu taurite	5-(Methoxymethylene) Te Waikawa Meldrum;Cabozantinib poke 56;Lenvatinib poke 79
Tau CAS	15568-85-1
Tau CAT	RF-PI1967
Tūnga Taonga	I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi	C8H10O5
Taumaha rāpoi	186.16
Te Whakarewa	132.0~134.0 ℃
Kiato	1.297±0.06 g/cm3
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Paura Kōwhai
1 H NMR Spectrum	E rite ana ki te Hanganga
Te Maama / Tikanga Tatauria	>97.0% (HPLC)
Nga poke katoa	<3.00%
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	Takawaenga o Lenvatinib Mesylate (CAS: 857890-39-2)

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku

Painga:

FAQ:

Taupānga:

5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione (CAS:15568-85-1) he takawaenga o Lenvatinib Mesylate (CAS: 857890-39-2).Ko Lenvatinib he rongoa mate pukupuku thyroid i whakawhanakehia e Eisai Corporation o Hapani (Waehere: E7080), no roto i te aukati o te waha maha-receptor tyrosine kinase (RTK) ka taea te aukati i te mahi kinase o te vascular endothelial growth factor (VEGF) Receptors VEGFR1 ( FLT1), VEGFR2 (KDR), me VEGFR3 (FLT4).Ka taea hoki e Lenvatinib te whakakore i te whakauru o etahi atu RTK i roto i te angiogenesis pathological, te tipu o te pukupuku, me te haere o te mate pukupuku engari mo o raatau mahi pūtau noa tae atu ki te fibroblast growth factor (FGF) nga kaiwhiwhi FGFR1, 2, 3, me te 4;te kaikawe tauwehe tipu i ahu mai i te platelet (PDGFR [alpha]), KIT, me te RET.[Nga Tohu]: He pai a Lenvatinib mo te maimoatanga o nga turoro o te mate pukupuku taikaro o te hokinga mai o te rohe, te momo metastasis ranei, te momo ahunga whakamua me te momo rerekee o te iodine-refractory radioactive.I te Hui-tanguru 13, 2015, i whakaaetia e te US FDA te tarukino anticancer Lenvatinib mo te maimoatanga o te mate pukupuku thyroid.Ko te Lenvatinib he aukati maha-whaanui-a-whaanui, he kaha ki te aukati i te VEGFR2 me te VEGFR3 (te kaikawe tauwehe endothelial vascular).Ko te ingoa hokohoko o Lenvatinib ko Lenvima.I te Haratua 20, 2015, i whakaaetia e te European Medicines Agency (EMA) a Lenvatinib mo te maimoatanga o te mate urutomo, te matatau o te rohe, te metastatic rereke ranei (papillary, follicular, Hurthle momo) mate pukupuku thyroid (DTC).I roto i te whakamatautauranga, ko te wa roa mo te oranga mo nga turoro o te DTC radioactive iodine-refractory DTC i tukuna ki a Lenvatinib he 18 marama ko te uara mo nga turoro e tango placebo he 3 marama anake.