Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Purity >99.0% (HPLC) Nintedanib Esylate Intermediate Factory
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) me te kounga teitei, te hanga arumoni.
Ingoa matū | Methyl 2-Oxoindoline-6-Carboxylate |
Nga kupu taurite | 2-Oxoindoline-6-Carboxylic Acid Methyl Ester;Methyl Oxindole-6-Carboxylate |
Tau CAS | 14192-26-8 |
Tau CAT | RF-PI1524 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C10H9NO3 |
Taumaha rāpoi | 191.19 |
Te Whakarewa | 184.0~190.0 ℃ |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Kowhai Maama ki te Paura Paraone |
1 H NMR Spectrum | E rite ana ki te Hanganga |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
Ngaronga i te whakamaroke | <1.00% |
Nga poke katoa | <1.00% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Nintedanib Esylate (CAS: 656247-18-6) |
Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) Huarahi Hangaia
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.
Ko te Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) he takawaenga i whakamahia hei whakarite Nintedanib Esylate (CAS: 656247-18-6).Ko te Nintedanib Esylate he kaha, he aukati angiokinase toru-a-waha i hangaia e Boehringer Ingelheim e aro ana ki nga huarahi proangiogenic me te pro-fibrotic i takawaenga e te kaikawe vascular endothelial growth factor, fibroblast growth factor receptor me te plateletderived growth factor receptors hapu, me te Src me te Flt-3 kinase.I whakaaetia a Nintedanib Esylate mo te maimoatanga o te idiopathic pulmonary fibrosis (IPF), he ahua ka pakaru haere nga ngongo i roto i te waa, e te US FDA i Oketopa 2014 me te EMA i te Hanuere 2015. I tukuna e te FDA te nintedanib esylate tere tere. , arotake matua, hua pani, me nga tohu tohu.I whakaaetia ano e te EMA i te marama o Whiringa-a-rangi 2014 mo te maimoatanga o te mate pukupuku o te puku kore-iti-iti me te docetaxel i muri i te chemotherapy raina tuatahi.