Molnupiravir N-1 CAS 2346620-55-9 COVID-19 Kounga Teitei
Molnupiravir Hokohoko me nga Kaiwaenga e Pa ana me te Kounga Kairangi
Uridine CAS 58-96-8
Cytidine CAS 65-46-3
Molnupiravir N-1 CAS 2346620-55-9
Molnupiravir (EIDD-2801) CAS 2349386-89-4
Ingoa matū | Molnupiravir N-1 |
Nga kupu taurite | ((3aR,4R,6R,6aR)-6-((E)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3, 4-d][1,3]dioxol-4-yl) methyl isobutyrate;Molnupiravir Intermediate;Molnupiravir Dimethyl Dioxol poke;Molnupiravir poke 11 |
Tau CAS | 2346620-55-9 |
Tau CAT | RF-PI310 |
Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
Tātai rāpoi | C16H23N3O7 |
Taumaha rāpoi | 369.37 |
Wairewa | Wairewa i roto i te DMSO |
Kiato | 1.51±0.1 g/cm3 |
Te Mahana Tukunga | Ambient |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura-White |
Ngaronga i te whakamaroke | ≤1.0% |
Te toenga i runga i te mura | ≤0.20% |
Te poke kotahi | ≤0.50% |
Nga poke katoa | ≤2.0% |
Nga Korewa Taamaha | ≤20ppm |
Maamaa | ≥98.0% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Molnupiravir (CAS 2349386-89-4) COVID-19 |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko Molnupiravir N-1 (CAS 2346620-55-9), ko te takawaenga o Molnupiravir (CAS 2349386-89-4) mo te maimoatanga o COVID-19.Ko te Molnupiravir (EIDD-2801) he ahua koiora-a-waha o te ribonucleoside tairitenga tino kaha e aukati ana i te tukuruatanga o nga huaketo RNA maha tae atu ki te SARS-CoV-2, te kaikorero o te COVID-19.Ko te EIDD-2801 (7 mg/kg; po; e rua nga wa ia ra mo te 3.5 ra) ka tino whakaiti i te kawenga huaketo whakaheke me te roanga o te kirikaa.Ko te Molnupiravir (EIDD-2801) he pai te whakamaarama i roto i te vivo i muri i te whakaurunga, ka puta ko te NHC kore utu anake i roto i te plasma.Ko te EIDD-2801 ka tino whakaheke i nga tohu hopuhopu MERS-CoV, te RNA viral, me te pathogenesis i raro i nga tikanga whakamaarama me nga tikanga rongoa moata.Ko te Molnupiravir (EIDD-2801, MK-4482) he prodrug bioavailable a-waha o te ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) me te mahi antiviral whanui whanui ki te SARS-CoV-2, MERS-CoV, SARS-CoV, me te kaikorero o te COVID-19.