Olmesartan Medoxomil CAS 144689-63-4 Purity >99.5% (HPLC) API Factory
Ruifu Chemical Supply Olmesartan Medoxomil Intermediates With High Quality:
4,5-Dimethyl-1,3-Dioxol-2-Kotahi (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Waikawa CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Ingoa matū | Olmesartan Medoxomil |
Nga kupu taurite | 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H- imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester;CS-866 |
Tau CAS | 144689-63-4 |
Tau CAT | RF-PI1730 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C29H30N6O6 |
Taumaha rāpoi | 558.60 |
Iwi Whakarewa | 180℃ (tikuri) |
Wairewa wai | Kore ki te wai;He iti te wairewa i roto i te DMSO |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura Cyrstalline Tata ma |
Tautuhinga | IR, HPLC, UV: Me Whakarite ki te Paerewa Tohutoro |
Te Maama / Tikanga Tatauria | >99.5% (HPLC i runga i te Paerewa Anhydrous me te Solvent-Free) |
Ngaronga i te whakamaroke | <0.50% |
Te toenga i runga i te mura | <0.10% |
Nga Taonga Paanga | |
Olmesartan RRT 0.2 | <0.50% |
Olmesartan Medoxoil Pūhui Pānga A. RRT 0.7 | <0.20% |
Olefinic poke RRT 1.6 | <0.50% |
N-Alkyl poke RRT 3.4 | <0.10% |
Tetahi atu poke | <0.10% |
Nga poke katoa | <0.50% |
Konga Taamaha (hei Pb) | <10ppm |
pH o Rongoa (2%, W/V) | 4.5 ki te 6.5 |
Paerewa Whakamatau | Paerewa hinonga;USP Paerewa |
Whakamahinga | API |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko te Olmesartan Medoxomil (CS-866) (CAS: 144689-63-4) he angiotensin II momo 1 (AT(1)) tino kaha me te whiriwhiri i te kaiwhaiwhakaaro me te IC50 o te 66.2 μM., ka whakamahia ki te maimoatanga o te toto toto tiketike.Ka whakamahia hei anti-hypertensive.Ka mahi a Olmesartan ma te aukati i te here o te angiotensin II ki nga kaiwhakawhiwhi AT1 i roto i nga uaua vascular.Ma te aukati i te here, kaua ki te whakahiatotanga o te angiotensin II, ka aukati a Olmesartan i nga urupare ture kino mo te renin secretion.Ko te Olmesartan Medoxomil he rongoa rongoa kua whakakorehia ki te metabolite kaha, olmesartan.I whakarewahia a Olmesartan Medoxomil ki te United States hei Benicar, he maimoatanga a-waha mo te whakaheke toto.