Palonosetron Hydrochloride CAS 135729-62-3 Purity >99.0% (HPLC) (T) API Factory

Whakaahuatanga Poto:

Ingoa matū: Palonosetron Hydrochloride

CAS: 135729-62-3

Te ahua: Paura Tioataata Maama ranei

Parakore: >99.0% (HPLC) (T)

Ko te Palonosetron Hydrochloride he tino kaha, he whiriwhiri me te kaha o te waha o te kaiwhakawhiwhi 5-HT3 antagonist e whakamahia ana hei aukati me te maimoatanga o te nausea me te ruaki (CINV).Whakahau.

Whakapā: Takuta Alvin Huang

Pūkoro/Wechat/WhatsApp: +86-15026746401

Inquiry: alvin@ruifuchem.com

Tukuna he imeera ki a matou

Taipitopito Hua

Hua e Pa ana

Tohu Hua

Whakaahuatanga:

Hoatu Arumoni Palonosetron Hydrochloride me nga Kaiwaenga Paanga:
(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API

Ngā Āhuatanga matū:

Ingoa matū	Palonosetron Hydrochloride
Nga kupu taurite	Palonosetron HCl;(S,S)-Palonosetron Hydrochloride;RS-25259;RS25259 197;(S)-2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-Hexahydro-1H-Benzo[de]isoquinolin-1-one Hydrochloride;(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-Hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride ;Aloxi;Onicit
Tau CAS	135729-62-3
Tau CAT	RF-API03
Tūnga Taonga	I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi	C19H24N2O·HCl
Taumaha rāpoi	332.87
Tikanga hei karo	Te werawera
Iwi Whakarewa	307℃ (tikuri)
Wairewa i te wai	Tino Wairewa ki te wai
Wairewa	He Iti Wairewa ki te Ewaro
Te Mahana Tukunga	Paemahana Ambient
COA & MSDS	Kei te waatea
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Te Paura Maama, Maama-Ma ranei
Palonosetron Hydrochloride	>99.0% (HPLC) (T)
Hurihuri Tau [α]20/D	-98.0°～-104.0°
Tautuhinga	Taapirihia te BiI7K4，Hanga Kowhai Kowhai Kowhai
Tautuhinga	TLC e rite ana ki te matū tohutoro
Tautuhinga	IR E rite ana ki te IR Paerewa
Tautuhinga	Te tautuhi hei Chloride
Wairewa	Ka whakarewa noa ki te wai, he iti te whakarewa ki te Methanol, he paku noa te wairewa ki te waiwaro, karekau ki te acetone
Te Maama me te Tae o te Otinga	Max.Kowhai Nama 2 Wairewa Paerewa Tae
pH Vaule	4.5~6.5 (10mg/ml)
Nga Taonga e Pa ana
Huihuinga A (KORE)	<0.10%
Pūhui Pānga B (Ene-NO)	<0.10%
Pūhui Pātahi C (S,R)	<0.10%
Pūhui Pātahi D (R,S)	<0.50%
Palonosetron Enantiomer	<0.10%
Pūhui Pātahi E (3-Ene)	<0.50%
Kotahi te poke kore i whakaingoatia	<0.10%
Wairewa toenga
Ewaro	<3000ppm
Tetrahydrofuran	<5000ppm
DMF	<880ppm
Hexane noa	<290ppm
Methyl Alcohol	<3000ppm
Isopropanol	<5000ppm
Methylbenzene	<890ppm
Wai	<0.30%
Te toenga i runga i te mura	<0.20%
Ngaronga i te whakamaroke	<1.00%
Nga Korewa Taamaha	<10ppm
Paerewa Whakamatau	United States Pharmacopoeia (USP);Te Hauora Hauora Pakeha (EP)
Whakamahinga	Palonosetron Hydrochloride API;5-HT3 Antagonist;CINV

Mōkī me te Rokiroki:

Mōkī: Pounamu, Paera Kaata, 25kg / Paera, kia rite ranei ki te hiahia a te kaihoko.

Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.

Painga:

FAQ:

Taupānga:

Ko te Palonosetron Hydrochloride (CAS: 135729-62-3) he rongoa hei aukati i te nausea me te ruaki, he momo hou e tino whiriwhiria ana, he antagonist kaikawe 5-HT3 tino hononga ka taea te aukati i te ruaki reflex centre peripheral neurons presynaptic 5-HT.Ko te hihikotanga o te kaiwhiwhi ka pa tika ki te punaha o te puku o te 5-HT.Ko te hihiko o te kaikawe kaikawe i hangaia e te mahi a te nerve afferent vagal i muri i te rohe, ka aukati i nga pito nerve vagus i roto i te kopu, ka aukati i nga tohu ki te 5-HT.Ka taea e te rohe whakaoho o te kaiwhiwhi te whakaheke i te mate o te nausea me te ruaki.Central haumanu mo te maimoatanga o te whakapeka nui emetogenic chemotherapy i whakaroa te whakapairuaki me te ruaki.Na te kaha o te rongoa, he iti te paanga o te taha, he roa te haurua o te ora (mo te 40 h), he inenga iti, me etahi atu, kua aro nui ki a ia.

Ki te 1,2,3,4-Tetrahydro-1-Naphthoic Acid hei mea timatanga, te wehenga, te amination, te whakaheke, te cyclization, te tote o te palonosetron hydrochloride granisetron.I whakaatuhia e nga rangahau haumanu ka taea te whakamahi humarie te palonosetron me nga corticosteroids, analgesics, antiemetics, antispasmodics me nga raau anticholinergic hei mea timatanga, te wehenga, te amination, te whakaheke, te cyclization, te tote o te palonosetron hydrochloride granisetron.