Paxlovid Boceprevir Intermediate CAS 565456-77-1 Assay ≥99.0%

Whakaahuatanga Poto:

Ingoa: (1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride

CAS: 565456-77-1

Te ahua: Ma ki te Paura-White

Whakamātautau: ≥99.0%

Takawaenga o PF-07321332 Paxlovid (CAS 2628280-40-8) me Boceprevir (CAS 394730-60-0)

Kounga Teitei, Hanganga Aromoni

Inquiry: alvin@ruifuchem.com

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Hua e Pa ana

Tohu Hua

Whakaahuatanga:

Whakarato Aromoni PF-07321332 Paxlovid Takawaenga e Pa ana ki te Kounga teitei
L-tert-Leucine (H-Tle-OH) CAS 20859-02-3
Caronic Anhydride CAS 67911-21-1
(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS 328086-60-8
6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9

Ngā Āhuatanga matū:

Ingoa matū	(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride
Nga kupu taurite	Methyl (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate Hydrochloride
Tau CAS	565456-77-1
Tau CAT	RF-PI318
Tūnga Taonga	I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi	C9H15NO2.ClH
Taumaha rāpoi	205.683
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Ma ki te Paura-White
Tautuhi A	IR: He rite ki te Matū Tohutoro
Tautuhinga B	Wā Pupuri: He rite ki te Matū Tohutoro
Enantiomer	≤0.15%
He poke e pa ana (na HPLC)
Te poke kore mohiotia	≤0.20%
Nga poke katoa	≤1.0%
Wai	≤0.50%
Te toenga i runga i te mura	≤0.10%
Nga Korewa Taamaha	≤20ppm
Te whakamatautau	≥99.0%
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	Takawaenga o PF-07321332 Paxlovid (CAS 2628280-40-8) me Boceprevir (CAS 394730-60-0)

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.

Painga:

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Taupānga:

(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride (CAS 565456-77-1) he pärönaki azabicyclohexane e whakamahia ana i roto i te whakarite o te mate hepatitis C. huaketo (HCV) NS3 serine protease inhibitor.Ko te takawaenga o PF-07321332 Paxlovid (CAS 2628280-40-8) me Boceprevir (CAS 394730-60-0).Ko te PF-07321332 he aukati kaha me te kaha o te waha SARS-CoV 3C-rite protease (3CLPRO) .Ko te PF-07321332 e whai ana ki te huaketo SARS-CoV-2 ka taea te whakamahi mo te tirotiro COVID-19.Ko te Boceprevir (INN, te ingoa hokohoko Victrelis) he aukati protease i whakamahia hei maimoatanga mo te mate mate pukupuku 1. Ka herea ki te HCV nonstructural 3 NS3 (HCV) waahi kaha.I whakawhanakehia e Schering-Plough, engari kei te whakawhanakehia inaianei e Merck mai i te wa i riro mai ai a Schering i te tau 2009. I whakaaetia e te FDA i te 13 o Mei, 2011.