Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9 Posaconazole Waenga Kounga Teitei
Whakawhiwhia wheketere me te tino parakore me te kounga pumau
Posaconazole Related Intermediates Commercial Production
Posaconazole CAS 171228-49-2
Posaconazole Intermediate POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2
Ingoa matū | Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate |
Nga kupu taurite | Posaconazole Intermediate |
Tau CAS | 184177-81-9 |
Tau CAT | RF-PI290 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C23H23N3O3 |
Taumaha rāpoi | 389.45 |
Kiato | 1.296 |
Tikanga Tukunga | I raro i te Mamahana Ambient |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paura Paraone ki te Paura Kerei |
Te Maama / Tikanga Tatauria | ≥99.0% (HPLC) |
Ngaronga i te whakamaroke | ≤0.50% |
Te toenga i runga i te mura | ≤0.20% |
Nga Korewa Taamaha | ≤20ppm |
Te poke kotahi | ≤0.50% |
Nga poke katoa | ≤1.0% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Waenga o Posaconazole (CAS 171228-49-2) |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko te Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate (CAS 184177-81-9) he Takawaenga o Posaconazole (CAS 171228-49-2).Ko te Posaconazole he whaanui whanui, reanga tuarua, triazole pūhui me te mahi antifungal.I whakaaetia mo te whakamahi rongoa i te United States i te marama o Hepetema 2006, a kei te waatea hei rongoa rongoa.Ko te Posaconazole he tarukino antifungal triazole i hokona i te United States e Schering-Plough i raro i te ingoa hokohoko Noxafil.Ka mahi a Posaconazole ma te whakararu i te kati kati o nga mekameka acyl o te phospholipids, ka whakaparahako i nga mahi o etahi punaha whaariki-membrane penei i te ATPase me nga enzyme o te punaha kawe irahiko, na reira ka aukati i te tipu o te harore.Ka mahia tenei ma te aukati i te whakahiatotanga o te ergosterol ma te aukati i te enzyme lanosterol 14a-demethylase me te whakaemi o te methylated sterol precursors.