Posaconazole Intermediate CAS 170985-85-0 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde
Nga Taonga Wheketere Posaconazole Related Intermediates, Acommercial Production
Posaconazole CAS 171228-49-2
Posaconazole Intermediate POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2
Ingoa matū | 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde |
Nga kupu taurite | N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide;N-[[(2S,3S)-2-phenylmethoxypentan-3-yl]amino]formamide;Posaconazole Intermediate;Posaconazole poke 33 |
Tau CAS | 170985-85-0 |
Tau CAT | RF-PI292 |
Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
Tātai rāpoi | C13H20N2O2 |
Taumaha rāpoi | 236.31 |
Tikanga Tukunga | Ka tukuna i raro i te pāmahana ambient |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paura Ma, Paura-Ma ranei |
Tautuhinga | H-NMR: He rite ki te Paerewa |
Ngaronga i te whakamaroke | ≤0.50% |
Te Maama / Tikanga Tatauria | ≥98.0% (HPLC) |
Nga poke pararopi | |
Tetahi poke kotahi | ≤0.50% |
Tapeke Parapara poke | ≤2.0% |
Nga Korewa Taamaha | ≤20ppm |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o te Posaconazole (CAS 171228-49-2) Kaituku Awhiowhio |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
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2-[(1S,2S)-1-Ethyl-2-(Phenylmethoxy)propyl]hydrazinecarboxaldehyde (CAS: 170985-85-0) he takawaenga nui o Posaconazole (CAS 171228-49-2).Ko te Posaconazole he tarukino antifungal triazole e whakamahia nuitia ana i roto i te maimoatanga o nga mate urutomo.Ko te Posaconazole he puhui triazole whanui whanui e kaha ana ki nga harore ma te aukati i te lanosterol 14α-demethylase enzyme.Ko te Posaconazole i ahu mai i te itraconazole.Ko ona hua rongoa he rite ki nga azoles, engari ka whakaritea ki te Itraconazole, he kaha ake te aukati i te C14 demethylation o te steroid, ina koa mo te Aspergillus.Ko Posaconazole, i whakarewahia i te UK, ko te mema hou o te akomanga azole o nga kaihoko antifungal kia tae ki te maakete.
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