Pregabalin CAS 148553-50-8 Purity >99.0% (HPLC) Antiepileptic API
Kaihanga me te Maamaa Teitei me te Hanga Aromoni
Ingoa matū: PregabalinCAS: 148553-50-8
Ko te Pregabalin he reanga tuarua o te rongoa antiepileptic (AED)
Ingoa matū | Pregabalin |
Nga kupu taurite | (S)-3-(Aminomethyl)-5-Methylhexanoic Acid;PD-144723;PD144723;CI 1008;CI-1008;Ririika |
Tau CAS | 148553-50-8 |
Tau CAT | RF-API57 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C8H17NO2 |
Taumaha rāpoi | 159.23 |
Iwi Whakarewa | 194.0~196.0 ℃ |
Wairewa i te wai | Kare e memeha ki te wai |
Wairewa | He Iti Wairewa ki te Ewaro |
Tikanga Tukunga | I raro i te Paemahana Ambient |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura Tioata-White |
Tautuhinga | IR: He rite ki te Matū Tohutoro |
Hurihuri Tauwhāiti | +10.0°~+13.0° (C=1, Wai) |
Ngaronga i te whakamaroke | <0.50% |
Te pungarehu whanariki | <0.10% |
Nga Taonga Paanga | poke A <0.15% |
Ko nga poke kaore i tohua i mua i te Pregabalin (whakamatautau A) <0.10% | |
Ko nga poke kore i tohua i muri i te Pregabalin (whakamatautau B ) <0.10% | |
Tapeke mo te whakamatautau A me B <0.50% | |
Pure Na HPLC R-Isomer | <0.15% |
Konga Taamaha (hei Pb) | <10ppm |
Pūhaumāota (Cl) | <0.05% |
Wairewa toenga | |
Waipiro Isopropyl | <5000ppm |
Ethyl Acetate | <5000ppm |
Tetrahydrofuran | <250ppm |
Isopropyl Etere | <500ppm |
Ewaro | <1000ppm |
Te Maama / Tikanga Tatauria | >99.0% (HPLC i runga i te tikanga maroke) |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Antiepileptic Drug API |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko te Pregabalin he rongoa antiepileptic tuarua-whakatupuranga (AED) e mohiotia ana me te ingoa waitohu rangatira o Lyrica (Pfizer, Tadworth) i te UK me te USA, he hanganga waikawa γ-amino butyric kei runga i tona hanganga ngota, he hua anticonvulsant, a he i pai te whakawhanakehia e te kamupene Pfizer mo te maimoatanga o te mamae neuropathic peripheral, te maimoatanga awhina ranei o te hopu i nga waahanga.Ko te Pregabalin he rongoa Anticonvulsant me te antiepileptic e whakamahia ana ki te rongoa i te epilepsy, te mamae neuropathic, te fibromyalgia, me te mate awangawanga whanui.Ko tana whakamahinga mo te mate pukupuku he rongoa taapiri mo te hopu i etahi waahanga me te kore ranei o te whaanui tuarua i roto i nga pakeke.I te Hakihea 2008, i whakaaetia e te US Food and Drug Administration (FDA) te pregabalin (ingoa hokohoko "Lyrica") mo te maimoatanga o te mamae neuropathic peripheral mate huka (DPN) me te neuralgia postherpetic (PHN) e rua nga mamae neuropathic tino noa.He tohu kua whakaaetia a Pregabalin, ka whakamahia nuitia mo te maimoatanga o te mate awangawanga whanui.He maha nga whakamatautau matapōkere, mata-rua, placebocontrolled trials i kitea he rongoa whai hua te pregabalin mo nga turoro me te mate awangawanga whanui me te mate awangawanga hapori.Te titration horopeta Te rongoa epilepsy-adjunctive: 25 mg bd mo nga ra e 7, me whakanui ake ma te 50 mg ia 7 ra;tiaki tikanga 300 mg ia ra, wehea ki 2 ranei 3 pota (max. 600 mg ia ra, wehea ki 2 ranei 3 pota).Te mate awangawanga whanui: 150 mg ia ra, ka wehea ki te 2, ki te 3 pota, mo nga ra e 7, kia piki ake ma te 150 mg ia 7 ra (max. 600 mg ia ra, ka wehea ki te 2 ki te 3 pota).Mena ka whakamutua te pregabalin, e taunaki ana kia whakahekehia i te iti rawa 1 wiki kia kore ai e tango ohorere.Whakatupato Nga turoro me nga ahuatanga ka paheke pea te encephalopathy.Ko nga turoro he nui te ngoikore o te ngakau.