Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Purity ≥98.5% (GC) Vonoprazan Fumarat Intermediate Factory
Whakaratohia te Vonoprazan Fumarate me te Waenga Takawaenga
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Ingoa matū | Pyridine-3-Sulfonyl Chloride |
| Nga kupu taurite | 3-Pyridinesulfonyl Chloride;3-Pyridylsulfonyl Chloride;m-Pyridinesulfonyl Chloride;Piperidine-3-Sulfonylchloride |
| Tau CAS | 16133-25-8 |
| Tau CAT | RF-PI540 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C5H4ClNO2S |
| Taumaha rāpoi | 177.61 |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | He wai kore tae, kowhai kowhai ranei |
| Te Maama / Tikanga Tatauria | ≥98.5% (GC) |
| Kohuatanga | 110.0~112.0℃/2mm Hg |
| Te poke kotahi | ≤0.50% |
| Nga poke katoa | ≤1.5% |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Takawaenga o Vonoprazan Fumarate (CAS: 1260141-27-2) |
Mōkī: Pounamu, 25kg / Barrel, i runga ranei i te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.
Ko Pyridine-3-Sulfonyl Chloride (CAS: 16133-25-8) he takawaenga o Vonoprazan Fumarate (CAS: 1260141-27-2).Ko te Vonoprazan Fumarate, i kitea, i whakawhanakehia e Takeda me Otsuka, i whakaaetia e te PMDA o Hapani i te Hakihea 2014, a ka tohuhia mo te maimoatanga o te mate pukupuku, te whewhe duodenal me te reflux esophagitis.Ko te Vonoprazan fumarate he momo mahi hou e kiia nei ko te konupora-whakataetae waikawa aukati, e whakataetae ana te aukati i te herenga o nga katote konupora ki te H+, K+-ATPase (e mohiotia ana ko te papu iraoho) i roto i te taahiraa whakamutunga o te hunanga waikawa pekitīlia i roto i nga pūtau parietal puku.Kaore a Vonoprazan i te aukati i te mahi Na +, K + -ATPase ahakoa i te 500 nga wa teitei ake i o ratou uara IC50 ki nga mahi H +, K + -ATPase pekitīlia.I tua atu, kaore te rongoa e pa ki te ahua huna o te kopu, kaore i rite ki nga PPI.
