(R)-(-)-3-Quinuclidinol CAS 25333-42-0 Purity ≥99.0% Chiral Purity ≥99.0%
| Ingoa matū | (R)-(-)-3-Quinuclidinol |
| Nga kupu taurite | (R)-3-Quinuklinol |
| Tau CAS | 25333-42-0 |
| Tau CAT | RF-CC117 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C7H13NO |
| Taumaha rāpoi | 127.18 |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Paura Ma, Paura-Ma ranei |
| Tautuhi RT (na GC) | Kia rite ki te Paerewa Tohutoro |
| Iwi Whakarewa | 212.0~224.0℃ |
| Hurihuri Tauwhāiti [α]D20 | -40.0°~ -48.0° |
| makuku (KF) | ≤0.50% |
| Te toenga i runga i te mura | ≤0.50% |
| Maamaa | ≥99.0% |
| Nga poke katoa | ≤1.00% |
| Chiral Pure | ≥99.0% |
| Enantiomer | ≤1.00% |
| Te whakamatautau | 98.0%～101.0% (i runga i te Waiwai) |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Pūhui Hira;Takawaenga Rongoa |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o (R)-(-)-3-Quinuclidinol (CAS: 25333-42-0) me te kounga teitei, e whakamahia nuitia ana i roto i te whakahiato waro, te whakahiato o nga takawaenga rongoa me Ko te whakahiatotanga o te Active Pharmaceutical Ingredient (API).(R)-(-)-3-Quinuclidinol ka taea te whakamahi hei takawaenga i roto i te whakahiatotanga o te API (CAS: 242478-38-2).(CAS: 242478-38-2) he rongoa antimuscarinic e whakamahia ana ki te rongoa i te tomi o te ngongo ka puta nga tohu o te auau, te tere, te kore e mau.(CAS: 242478-38-2) Ko te M3 muscarinic antagonist receptor i whakawhanakehia, i whakarewahia mo te maimoatanga o te pukupuku tino kaha (pollakiuria) i Uropi.Ko nga kaiwhakawhiwhi M3 kua uru ki roto i nga uaua maeneene maeneene o te ngongo ngongo, a, kua whakapaehia ano he mahi a nga kaiwhakawhiwhi M2 na to ratou mana ki te uaua detrusor.Ko te whakahiatotanga o te solifenacin ko te whakarite i te racemic 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline ma te cyclization o N-(2-Phenylethyl)benzamide, me te tauhohenga o muri mai me te ethyl chloroformate me te transesterification me (R) -3-Quinuclidinol .Ka taea e Chiral chromatography te wehe i te diastereomer e hiahiatia ana.I tua atu, ka tukuna te 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline ki te whakatau mata me te (+) -Tartaric Acid i mua i te maimoatanga me te ethyl chloroformate me te whakawhitinga o muri mai.
