Remdesivir GS-5734 CAS 1809249-37-3 COVID-19 API Kounga Teitei

Whakaahuatanga Poto:

Ingoa matū: Remdesivir (GS-5734)

CAS: 1809249-37-3

Te ahua: Paura Maama ki te Paura-Ma

Whakatau: 98.0%~102.0%

Remdesivir mo te maimoatanga o COVID-19

API Kounga Teitei, Hanganga Tauhokohoko

Inquiry: alvin@ruifuchem.com

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Hua e Pa ana

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Whakaahuatanga:

Kaihanga Kaihanga Remdesivir me nga Kaiwawao e pa ana ki te Kounga Kairangi
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Takawaenga CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4] triazine CAS 1770840-43-1

Ngā Āhuatanga matū:

Ingoa matū	Remdesivir
Nga kupu taurite	GS-5734;2-ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano -3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Tau CAS	1809249-37-3
Tau CAT	RF-API96
Tūnga Taonga	Kei roto i nga taonga, ka eke ki te rau kirokaramu
Tātai rāpoi	C27H35N6O8P
Taumaha rāpoi	602.58
Kiato	1.47±0.1 g/cm3
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Te Maama ki te Paura Maamaa Maamaa
Tautuhi A	IR: Ko te tuāwhiorangi whakauru infrared o te hua kia rite ki tera o te matū tohutoro
Tautuhinga B	He rite te wa pupuri HPLC ki te matū tohutoro
Hurihuri Tauwhāiti	-19.0° ~ -22.0°
Wairewa	Solunle i roto i te Methanol, He iti te Wairewa i roto i te Ethanol, He iti te Rere ki te Acetonitrile, Kare i Rirewa ki te Wai
Nga Taonga Paanga
Te poke takitahi	≤0.10%
Nga poke katoa	≤1.0%
RD-3.1	≤0.10%
RD-C	≤0.10%
RD-D	≤0.10%
RD-E	≤0.10%
RP-Isomer	≤0.10%
Nitrophenol	≤0.10%
Wairewa toenga
Mewaro Dichloride	≤6000ppm
Acetone	≤5000ppm
Waipiro Isopropyl	≤5000ppm
Acetonitrile	≤410ppm
Dichloromethane	≤600ppm
Methyl tert Butyl Ether	≤5000ppm
Ethyl Acetate	≤5000ppm
Tetrahydrofuran	≤720ppm
n-Heptane	≤5000ppm
Te whakamatautau	98.0%~102.0% (Kua tatauhia i runga i te whakamaroke)
Tatau Aerobic Tapeke
Huakita Aerobic	≤100cfu/g
Te rewena me te Maaka	≤10cfu/g
E. Porowhita	He kino
Endotoxin huakita	≤1.0EU
Nga Korewa Taamaha	≤20ppm
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	API, COVID-19

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.

Painga:

FAQ:

Taupānga:

Ko Remdesivir (CAS 1809249-37-3), i hokona i raro i te ingoa tohu Veklury, he rongoa antiviral whanui whanui i whakawhanakehia e te kamupene biopharmaceutical Gilead Sciences.Ka tukuna ma te werohanga ki roto i te uaua.I te wa o te mate COVID-19, i whakaaetia te remdesivir, i whakamanahia ranei mo te whakamahi ohorere ki te rongoa COVID-19 i roto i te 50 whenua.Ko nga aratohu kua whakahoutia mai i te Whakahaere Hauora o te Ao i te marama o Whiringa-a-rangi 2020 kei roto ko te kupu whakahau mo te whakamahi i te Remdesivir mo te maimoatanga o COVID-19.I hangaia a Remdesivir ki te rongoa i te mate hepatitis C, a i muri mai i tirotirohia mo te mate huaketo Ebola me nga mate huaketo Marburg i mua i te ako hei rongoa i muri i te mate mo te COVID-19.Ko te nuinga o nga paanga kino i roto i nga kaitūao hauora ko te piki ake o nga taumata toto o nga enzyme ate (he tohu o nga raruraru ate).Ko te tino paanga ki te hunga whai COVID-19 ko te nausea.Ko nga paanga o te taha ko te mumura ate me te hohenga e pa ana ki te whaowhia me te nausea, te whakaheke toto, me te werawera.Ko te Remdesivir he prodrug e kii ana ki te tuku intracellular te tuku o te GS-441524 monophosphate me te huringa koiora o muri mai ki te GS-441524 triphosphate, he ribonucleotide analogue inhibitor o te RNA polymerase viral.