Remdesivir Intermediate CAS 1354823-36-1 COVID-19 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester

Whakaahuatanga Poto:

N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester

CAS: 1354823-36-1

Takawaenga o Remdesivir (CAS 1809249-37-3) mo te maimoatanga o COVID-19

Kounga Teitei, Hanganga Aromoni

Inquiry: alvin@ruifuchem.com

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Whakaahuatanga:

Kaihanga Kaihanga Remdesivir me nga Kaiwawao e pa ana ki te Kounga Kairangi
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Takawaenga CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4] triazine CAS 1770840-43-1

Ngā Āhuatanga matū:

Ingoa matū	N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester
Nga kupu taurite	Remdesivir Intermediate;Remdesivir Side Chain;Remdesivir p-NitroPhenoxy L-Alanine poke;Remdesivir poke 4;Remdesivir-002;(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)-phosphoryl)-amino)propanoate
Tau CAS	1354823-36-1
Tau CAT	RF-PI297
Tūnga Taonga	Kei roto i nga taonga, ka eke ki te rau kirokaramu
Tātai rāpoi	C21H27N2O7P
Taumaha rāpoi	450.42
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Ma ki te paura tata ma
Tautuhinga	IR, HPLC
Ngaronga i te whakamaroke	≤1.0%
Te poke kotahi	≤0.50%
Nga Korewa Taamaha	≤20ppm
Maamaa	≥98.0%
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	Takawaenga o Remdesivir (CAS 1809249-37-3);COVID-19

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.

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Taupānga:

N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester (CAS 1354823-36-1, e mohiotia ana ko Remdesivir Impurity 4) he mekameka taha phosphoramidate e whakamahia ana mo te whakarite i te Remdesivir (CAS). 1809249-37-3, GS-5734), he rongoa rangahau pareketo hou mo te maimoatanga o te mate huaketo Ebola me nga mate wheori Marburg, ka kitea hoki e whakaatu ana i nga mahi patu huaketo ki nga coronaviruses (hei tauira, SARS-Cov-2/ Covid-19).I te pakarutanga o te mate Coronavirus hou 2019 (COVID-19), ko Remdesivir (CAS 1809249-37-3) tetahi o nga hua rangahau e pa ana ki te COVID-19.Ko Remdesivir, i hokona i raro i te ingoa tohu Veklury, he rongoa antiviral whanui whanui i whakawhanakehia e te kamupene biopharmaceutical Gilead Sciences.Ka tukuna ma te werohanga ki roto i te uaua.I te wa o te mate COVID-19, i whakaaetia a Remdesivir, i whakamanahia ranei mo te whakamahi ohorere ki te rongoa COVID-19 i roto i te 50 whenua.Ko nga aratohu kua whakahoutia mai i te Whakahaere Hauora o te Ao i te marama o Whiringa-a-rangi 2020 kei roto ko te kupu whakahau mo te whakamahi i te Remdesivir mo te maimoatanga o COVID-19.