Remdesivir Intermediate CAS 1911578-98-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate

Whakaahuatanga Poto:

Ingoa Matū: 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate

CAS: 1911578-98-7

Te ahua: Ma ki te Paura-WhiteMaamaa: ≥98.0%

Takawaenga o Remdesivir (CAS 1809249-37-3) COVID-19

Kounga Teitei, Hanganga Aromoni

Inquiry: alvin@ruifuchem.com

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Whakaahuatanga:

Kaihanga Kaihanga Remdesivir me nga Kaiwawao e pa ana ki te Kounga Kairangi
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Takawaenga CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4] triazine CAS 1770840-43-1

Ngā Āhuatanga matū:

Ingoa matū	2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate
Nga kupu taurite	N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester;Remdesivir Intermediate;Remdesivir-001;Remdesivir poke 21
Tau CAS	1911578-98-7
Tau CAT	RF-PI303
Tūnga Taonga	Kei roto i nga taonga, ka eke ki te rau kirokaramu
Tātai rāpoi	C21H27N2O7P
Taumaha rāpoi	495.38
Kiato	1.2g/cm3
Iwi Whakarewa	92.0~96.0℃(marama)
Kohuatanga	356.7 ℃ i te 760 mmHg
Tikanga Tukunga	Ka tukuna i raro i te pāmahana ambient
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Ma ki te Paura-White
Spectrum Infrared	He rite ki te Hanganga
Maamaa	≥99.0%
Ngaronga i te whakamaroke	≤0.50%
Te poke kotahi	≤0.50%
Nga poke katoa	≤1.0%
Nga Korewa Taamaha	≤20ppm
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	Takawaenga o Remdesivir (CAS 1809249-37-3)

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.

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Taupānga:

Ko te 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate (CAS 1911578-98-7) he takawaenga matua matatau i roto i te whakarite o nga tairitenga e pa ana ki a Remdesivir.Ko te Remdesivir he monophosphoramidate prodrug o te tairitenga adenosine, he maataki whakamaarama whaanui-a-whanui me te mahi in vitro ki te SARS coronavirus, MERS coronavirus me, tata nei, Covid-19.Ko te Remdesivir te nuinga i whakawhanakehia hei rongoa mo nga mate filovirus penei i te mate huaketo Ebola, huaketo Marburg ranei.I muri mai, i kitea a Remdesivir ki te whakaatu i te mahi pareketo ki etahi atu wheori RNA kotahi-paepae penei i te rewharewha syncytial, Nipah virus, Hendra virus, Junin virus, Lassa fever virus me nga coronaviruses (tae atu ki te MERS me te SARS).Ina tata nei kei te rangahauhia hei rongoa pai mo te maimoatanga o te COVID-19 (he huaketo momo SARS hou).Ko te Remdesivir, i whakawhanakehia e Gilead Sciences, he adenosine prodrug ka huri ki tona ahua kaha GS-441524 e whakararu ana i te mahi a te RNA-whakawhirinaki RNA polymerase me te karo i te panui e te exoribonuclease viral (ExoN), ka heke te hanga RNA viral.