Remdesivir Metabolite (GS-441524) CAS 1191237-69-0 COVID-19
Kaihanga Kaihanga Remdesivir me nga Kaiwawao e pa ana ki te Kounga Kairangi
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Ingoa matū | (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-Dihydroxy-5-(Hydroxymethyl)tetrahydrofuran- 2-Carbonitrile |
Nga kupu taurite | GS-441524;Remdesivir Metabolite;Remdesivir Intermediate;Nucleosid o Remdesivir;EVO984;Remdesivir O-Desphosphate Analogue;Remdesivir Related Compound 6 poke |
Tau CAS | 1191237-69-0 |
Tau CAT | RF-PI299 |
Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
Tātai rāpoi | C12H13N5O4 |
Taumaha rāpoi | 291.26 |
Wairewa | Wairewa i roto i te DMSO |
Storag | Wahi maroke Matao |
Tikanga Tukunga | Ka tukuna i raro i te pāmahana ambient |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te paura tata ma |
Maamaa | ≥99.0% |
Arepa-Isomer | ≤0.30% |
O-Bn Derivative | ≤0.30% |
N-Bn Putanga | ≤0.30% |
Mōrahi Kore kotahi | ≤0.30% |
Ngaronga i te whakamaroke | ≤1.0% |
Te toenga i runga i te mura | ≤0.50% |
Nga Korewa Taamaha | ≤20ppm |
Arsenic | ≤2ppm |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Remdesivir (CAS 1809249-37-3);COVID-19 |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko te Remdesivir nucleoside analogue (GS-441524, CAS 1191237-69-0) he mea tino nui ki te whakahiato o Remdesivir triphosphate (1355149-45-9) me Remdesivir (1809249-37-3).Ko te GS-441524 he rongoa whakamarumaru nucleoside analogue i hangaia e Gilead Sciences.Ko tenei tairitenga ūkuikui te nuinga he puhui kaha ki te rongoa i te Ebola me te COVID-19.Koia te metabolite plasma matua o te antiviral prodrug remdesivir, a he haurua te ora mo te 24 haora i roto i nga turoro tangata.Ko te Remdesivir me te GS-441524 i kitea e whai hua ana i roto i te vitro ki nga riipene coronavirus feline e haangai ana mo te feline infectious peritonitis (FIP), he mate whakamate e pa ana ki nga ngeru whare.