(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1 Ibrutinib Intermediate Purity >99.0% (GC) Atahanga Whakaatu

(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1 Ibrutinib Waenga Parakore >99.0% (GC)

Whakaahuatanga Poto:

Ingoa matū: (S)-1-Boc-3-Hydroxypiperidine

CAS: 143900-44-1

Maamaa Chiral: >99.0% (GC)

Te Maamaa: >99.0% (GC)

Te ahua: Paura Ma, Tioata ranei

Takawaenga o Ibrutinib (CAS: 936563-96-1)

Kounga Teitei, Hanganga Aromoni

E-Mail: alvin@ruifuchem.com

Tukuna he imeera ki a matou

Taipitopito Hua

Hua e Pa ana

Tohu Hua

Whakaahuatanga:

Ngā Āhuatanga matū:

Ingoa matū	(S)-1-Boc-3-Hydroxypiperidine
Nga kupu taurite	(S)-1-(tert-Butoxycarbonyl)-3-Hydroxypiperidine;(S)-1-Boc-3-Piperidinol
Tau CAS	143900-44-1
Tau CAT	RF-CC299
Tūnga Taonga	I roto i te Stock, Production Raukaha 20 Tons / Marama
Tātai rāpoi	C10H19NO3
Taumaha rāpoi	201.27
Iwi Whakarewa	52.0~56.0℃
Wairewa	Wairewa ki Methanol
Hurihuri Tau [a]20/D	+9.0°~+11.0° (C=1 in Chloroform)
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Paura Ma, Tioata ranei
Chiral Pure	>99.5% (GC)
Te Maamaa	>99.5% (GC)
Wai (KF)	≤0.50%
Mewaro (GC)	≤50ppm
Ewaro (GC)	≤50ppm
DCM (GC)	≤500ppm
3-Hydroxypiperidine	≤0.10%
3-Hydroxypyridine	≤0.20%
1-Boc-3-Piperidone	≤0.10%
1-Boc-4-Hydroxypiperidine	≤0.10%
1.96 RRT	≤0.20%
Tetahi poke kore i tohua	≤0.10%
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	Takawaenga Rongoa;Pūhui Hira

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.

Painga:

FAQ:

Taupānga:

(S)-1-Boc-3-Hydroxypiperidine (CAS: 143900-44-1) he takawaenga chiral nui mo te whakahiato o Ibrutinib (CAS: 936563-96-1).Ko te Ibrutinib he momo aukati Bruton tyrosine kinase (BTK), ka taea te whakamahi mo te maimoatanga o te mate pukupuku lymphocytic tawhito (CLL) me te lymphoma pūtau koroka (MCL).Ko te MCL me te CLL no te lymphoma kore-Hodgkin B-cell, he uaua ki te rongoa me te ngawari ki te hoki mai.Ko te whakamaarama matū matū noa kaore he whaainga, he maha nga wa e 3, e 4 nga tauhohenga kino.Ka taea e nga lymphocytes Ibrutinib me B te whai ki te BTK e tika ana mo te hanga, te rereketanga, me te tuku korero, te aukati i te mahi BTK e kore e taea te huri, me te aukati i te tipu o nga pūtau puku me te ora.Ka taea e Ibrutinib te tere tere i muri i te whakahaere a-waha, i roto i te 1 ~ 2h ka tae ki te nui o te toto toto, ko nga tauhohenga kino no te kotahi, e rua ranei, na reira, ka waiho a Ibrutinib hei whiringa hou mo te maimoatanga o CLL me MCL.