(S)-3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Purity ≥99.0% ee≥99.0% Palonosetron Hydrochloride Intermediate
Hoatu Arumoni Palonosetron Hydrochloride me nga Kaiwaenga Paanga:
(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API
| Ingoa matū | (S)-3-Aminoquinuclidine Dihydrochloride |
| Nga kupu taurite | (S)-(-)-3-Aminoquinuclidine 2 HCL |
| Tau CAS | 119904-90-4 |
| Tau CAT | RF-CC112 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C7H16Cl2N2 |
| Taumaha rāpoi | 199.12 |
| Kiato | 1.24g/cm3 |
| Iwi Whakarewa | 260℃ |
| Kohuatanga | 470.4 ℃ i te 760mmHg |
| Wairewa i te wai | Wairewa |
| Tikanga Tukunga | Ka tukuna i raro i te pāmahana ambient |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Ma ki te Maama Kowhai Kowhai Tioata Paura |
| IR | Ko te Absorption Spectra e rite ana ki te Tohutoro |
| Tauhohenga Chloride | Tauhohenga Pai |
| Pure (HPLC) | ≥98.0% |
| Ngaronga i te whakamaroke | ≤0.50% |
| Hurihuri Tauwhāiti [α]D20 | -22.0°~ -26.0° (C=1, H2O) |
| Nga Korewa Taamaha | ≤20ppm |
| Rokiroki | 5-8 ℃ Te hau |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Palonosetron Hydrochloride (CAS: 135729-62-3) Takawaenga |
(S)-3-Aminoquinuclidine Dihydrochloride (CAS: 119904-90-4) Huarahi Hangaia
Mōkī: Pounamu, Peeke konumohe konumohe, Paera Kaata, 25kg / Paera, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o (S) -3-Aminoquinuclidine Dihydrochloride (CAS: 2133-40-6) me te kounga teitei.He takawaenga rongoa i te nuinga o te wa i roto i te whakahiatotanga o Palonosetron Hydrochloride (CAS: 135729-62-3).
Ko te Palonosetron Hydrochloride (CAS: 135729-62-3) he rongoa hei aukati i te nausea me te ruaki, he momo hou e tino whiriwhiria ana, he antagonist kaikawe 5-HT3 tino hononga ka taea te aukati i te ruaki reflex centre peripheral neurons presynaptic 5-HT.Ko te hihikotanga o te kaiwhiwhi ka pa tika ki te punaha o te puku o te 5-HT.Ko te hihiko o te kaikawe kaikawe i hangaia e te mahi a te nerve afferent vagal i muri i te rohe, ka aukati i nga pito nerve vagus i roto i te kopu, ka aukati i nga tohu ki te 5-HT.Ka taea e te rohe whakaoho o te kaiwhiwhi te whakaheke i te mate o te nausea me te ruaki.Central haumanu mo te maimoatanga o te whakapeka nui emetogenic chemotherapy i whakaroa te whakapairuaki me te ruaki.Na te kaha o te rongoa, he iti te paanga o te taha, he roa te haurua o te ora (mo te 40 h), he inenga iti, me etahi atu, kua aro nui ki a ia.Ki te 1,2,3,4-tetrahydro-1-naphthoic acid hei mea timatanga, te wehenga, te amination, te whakaheke, te cyclization, te tote o te palonosetron hydrochloride granisetron.I whakaatuhia e nga rangahau haumanu ka taea te whakamahi humarie te palonosetron me nga corticosteroids, analgesics, antiemetics, antispasmodics me nga raau anticholinergic hei mea timatanga, te wehenga, te amination, te whakaheke, te cyclization, te tote o te palonosetron hydrochloride granisetron.
