Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Purity >99.0% (HPLC) Factory Kounga Teitei
Whakaratohia nga Kaiwaenga e Pa ana ki te Sitagliptin Phosphate Monohydrate:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Waikawa CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Wakawa Butyric CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Takawaenga CAS 486460-21-3
Ingoa matū | 3-(Trifluoromethyl)-5,6,7,8-tetrahydro- [1,2,4] triazolo [4,3-a] pyrazine Hydrochloride |
Nga kupu taurite | Sitagliptin Triazole Hydrochloride;Sitagliptin Intermediate A |
Tau CAS | 762240-92-6 |
Tau CAT | RF-PI1193 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C6H7F3N4·HCl |
Taumaha rāpoi | 228.60 |
Te Whakarewa | 236.0~246.0 ℃ |
Wairewa | Wairewa ki Methanol |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura Tioata-White |
Te tautuhi na HPLC | Ko te wa pupuri o te tauira he rite ki te paerewa tohutoro |
Te tautuhi na IR | Ka tutuki |
Ngaronga i te whakamaroke | <0.50% |
Nga Taonga Paanga | |
Tetahi poke kotahi | <0.50% |
Nga poke katoa | <1.00% |
Nga Korewa Taamaha | <20ppm |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride (CAS: 762240-92-6) he takawaenga o Sitagliptin Phosphate Monohydrate ( CAS: 654671-77-9), he aukati DPP4 whiriwhiri-a-waha-a-waha i kitea na roto i te arotautanga o te karaehe o nga aukati DPP4 i ahu mai i te β-aminoacid.Ka whakahekehia te mahi DPP4 i roto i te wa roa i muri i te whakahaerenga kotahi i ia ra, ka pupuri i nga taumata tohanga o te GIP me te GLP1 i muri i nga kai i roto i nga rangahau whakapeka me te roa me te whakaheke i nga taumata huka toto kaore he pikinga nui o te hypoglycaemia.Ka whakamahia te Sitagliptin Phosphate (STG) ki te rongoa i te momo DM 2 na te mea ka pai ake te whakahaere glycemic ma te whakanui ake i nga taumata o nga homoni incretin kaha, GLP-1 (peptide-1) me GIP (glucose-dependent insulinotropic peptide).I whakamanahia a STG e te FDA i te tau 2006.