Telmisartan CAS 144701-48-4 Purity >99.5% (HPLC) API Factory
Ruifu Chemical Supply Telmisartan Intermediates With High Pure
Telmisartan CAS 144701-48-4
Methyl 2-(p-Tolyl)benzoate CAS 114772-34-8
2-(p-Tolyl)Wakawa benzoic CAS 7148-03-0
Telmisartan Benzimidazole Acid CAS 152628-03-0
Telmisartan Methyl Ester CAS 528560-93-2
Methyl 2-[4-(Bromomethyl)phenyl]benzoate CAS 114772-38-2
Methyl 4-(Butyrylamino)-3-Methyl-5-Nitrobenzoate CAS 152628-01-8
2-n-Propyl-4-Methyl-6-(1-Methylbenzimidazole-2-yl)benzimidazole CAS 152628-02-9
Ingoa matū | Telmisartan |
Nga kupu taurite | 4'-[[4-Methyl-6-(1-Methyl-1H-Benzimidazol-2-yl)-2-Propyl-1H-Benzimidazol-1-yl]methyl]biphenyl-2-Carboxylic Acid;4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-Benzimidazol]-1'-yl)methyl]-[1,1'-Biphenyl]-2-Warokawa Waikawa |
Tau CAS | 144701-48-4 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C33H30N4O2 |
Taumaha rāpoi | 514.63 |
Iwi Whakarewa | 261.0~263.0 ℃ |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Te Paura Maama, Maama-Ma ranei |
Te kakara | Te ahuatanga |
Wairewa | He iti te memeha ki te Methylene Chloride, He iti te Souble ki te Methanol, He Korekore ki te Wai, Ka memeha ki te 1M Solution Hydroxide |
IR Identification | Me Taurite ki te RS Infrared Absorption |
Tautuhinga HPLC | Ko te Wa Pupuri o Major Peak Me Taurite ki te RS |
Te Maama / Tikanga Tatauria | >99.5% (HPLC) |
Ngaronga i te whakamaroke | <1.00% |
Te toenga i runga i te mura | <0.10% |
Nga Taonga Paanga | |
Telmisartan Related Compound A | <0.10% |
Telmisartan Amide | <0.10% |
Telmisartan Related Compound B | <0.10% |
Telmisartan Diacide | <0.10% |
Telmisartan Tert-Butyl Ester | <0.20% |
Telmisartan Unknown poke | <0.20% |
Te poke kore | <0.10% |
Nga poke katoa | <1.00% |
Wairewa toenga | |
Mewaro | <0.30% |
Ewaro | <0.50% |
Methylene Dichloride | <0.06% |
n-Hexane | <0.029% |
Acetic Acetic Ethyl Ester | <0.50% |
Toluene | <0.089% |
Waikawa Acetic | <0.50% |
Nga Korewa Taamaha | <10ppm |
Arsenic (As) | <1.00ppm |
Arataki (Pb) | <1.00ppm |
Cadmium (Cd) | <1.00ppm |
Rahi Matūriki | D90 Kaua e Neke atu i te 15μm |
Kiato Nui (g/cc) | 0.11~0.20 |
Kiato Paopao (g/cc) | 0.22~0.30 |
Pesticide toenga | He kino |
Tatau Pereti Tapeke | <1000cfu/g |
Te rewena me te pokepokea ai | <100cfu/g |
E. Coli | He kino |
Haramona | He kino |
Paerewa Whakamatau | Paerewa hinonga;USP 41 Paerewa |
Whakamahinga | API |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko te Telmisartan (CAS: 144701-48-4) he whakaputanga benzimidazole me te angiotensin II kore-peptide kaiawhina antagonist me nga taonga antihypertensive.Ko te Telmisartan te whakahē i te angiotensin II e herea ana ki te kaiwhakawhiwhi momo AT1, kei roto i nga uaua maeneene me te repe adrenal.Ko te antagonism ka hua ki te vasodilation me te aukati i te hanga aldosterone-a-angiotensin II-mediated, na te mea ka heke te konutai me te wai tae atu ki te piki haere o te konutai konupora e arahi ana ki te heke o te pehanga toto.Ko te Telmisartan he momo hou o nga raau taero toto toto, ka whakamahia anake, ka whakakotahi ranei me etahi atu karaehe antihypertensives mo te maimoatanga o te whakaheke toto.I hangaia a Telmisartan e te kamupene rongoa Tiamana a Boehringer Ingelheim;riro te reira i te German patent EP502,314 i roto i 1991, i whakaaetia tuatahi ki te tomo i te mākete Amerika i roto i te Whiringa 1998, a ka tomo Tiamana, Philippines, Ahitereiria, Belgium, Ingarangi, me etahi atu mākete.