Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0%~101.0% API Factory High Pure
Whakarato Temozolomide me nga Takawaenga Paanga:
Temozolomide CAS: 85622-93-1
4(5)-Amino-5(4)-Imidazolecarboxamide CAS: 360-97-4
5(4)-Amino-4(5)-Imidazolecarboxamide Hydrochloride CAS: 72-40-2
| Ingoa matū | Temozolomide |
| Nga kupu taurite | 3,4-Dihydro-3-Methyl-4-Oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-Carboxamide |
| Tau CAS | 85622-93-1 |
| Tau CAT | RF-API29 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C6H6N6O2 |
| Taumaha rāpoi | 194.15 |
| Iwi Whakarewa | 212℃ Hakihea. |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Ma ki te Paura Mawhero Maama |
| Tautuhinga | Na IR, HPLC |
| Wairewa toenga | Dimethyl Sulphoxide ≤0.50% |
| Nga Taonga Paanga | |
| AIC poke | ≤0.10% |
| Te poke kotahi | ≤0.10% |
| Okioki Nga poke kore mohiotia | ≤0.30% |
| Nga poke katoa | ≤0.30% |
| Nga Korewa Taamaha | ≤10ppm |
| Ngaronga i te whakamaroke | ≤0.50% |
| Te toenga i runga i te mura | ≤0.10% |
| Te whakamatautau | 99.0%~101.0% (HPLC i runga i te whakamaroke) |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Mahinga Rongoa Hohe (API) |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o Temozolomide (CAS: 85622-93-1) me te kounga teitei.Ko te Temozolomide (TMZ) he kaihoko alkylating waha e whakamahia ana ki te rongoa i a Glioblastoma Multiforme (GBM) me Astrocytomas, Metastatic Melanoma.
Ko te Temozolomide te rongoa tuatahi mo te imidazole me te tetrazine-class anticancer no te reanga tuarua o te kaihoko alkylating me te mahi antitumor me te kore e whakahohehia te ate i muri i te whakahaere waha.Ko te ahua o te kuhu ngawari ki roto i te arai toto-roro, te pai o te manawanui me te kore e uru atu ki etahi atu raau taero paitini, me te whai huatanga ki te radiotherapy e tika ana mo te rongoa i te hokinga mai o te glioma kino i muri i te maimoatanga tikanga penei i nga pukupuku glioblastoma multiforme, astrocytoma degenerative ranei.He rongoa rarangi tuatahi mo te maimoatanga o te melanoma metastatic.
Ko te Temozolomide i whakahiato tuatahi e Cancer Research UK Group, katahi ka tukuna ki te Kamupene Schering-Plough (United States) mo te whanaketanga.He hanganga matū hou, no roto i te pärönaki wha-imidazole.I te tau 1999, kua whakaaetia kia uru atu ki te maakete i EU me te US ko te tohu e whakaaetia ana i Amerika ko te nuinga mo te maimoatanga tuarua o te glioblastoma multiforme me te gliomas whetu degenerative me nga tohu kua whakaaetia mo te EU mo te rongoa i te whakawhanaketanga o te glioblastoma multiforme ranei. kua tukuna kētia ki te maimoatanga tikanga.Ko te kaha o te temozolomide ki te rongoa i te glioblastoma multiforme kua nui ake te whakanui i Uropi.
