Tenofovir Alafenamide Hemifumarate TAF CAS 1392275-56-7 API Factory Anti-HIV Kounga Teitei

Whakaahuatanga Poto:

Ingoa: Tenofovir Alafenamide Hemifumarate (TAF)

CAS: 1392275-56-7

Maama ki te Tata Maama Tioata, Tioata Paura ranei

Whakatau: 98.0%~102.0%

He prodrug mo Tenofovir, i whakamahia i roto i te rongoa whakakotahi mo te maimoatanga o te mate HIV-1

Kounga Teitei, Hanganga Aromoni

Inquiry: alvin@ruifuchem.com


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Whakaahuatanga:

Ngā Āhuatanga matū:

Ingoa matū Tenofovir Alafenamide Hemifumarate
Nga kupu taurite TAF;GS-7340 Hemifumarate
Tau CAS 1392275-56-7
Tau CAT RF-API91
Tūnga Taonga Kei roto i nga taonga, ka eke ki te rau kirokaramu
Tātai rāpoi C25H33N6O9P
Taumaha rāpoi 592.55
Paemahana Rokiroki Hirihia ki te maroke, te pāmahana rūma
Waitohu Ruifu Chemical

Whakatakotoranga:

Tūemi Whakatakotoranga
Te ahua Maama ki te Tata Maama Tioata, Tioata Paura ranei
Wairewa Wairewa i roto i te Dimethylformamide, me te Methanol;He iti te wairewa ki te wai me te THF;He iti te whakarewa i roto i te Acetonitrile me te Insoluble i te Dichloromethane me te Toluene
Tautuhi A Ko te IR absorption spectrum kia rite ki te tohutoro
Tautuhinga B Ko te wa pupuri o te tihi nui o te otinga tauira i roto i te chromatogram whakatau ihirangi e rite ana ki tera o te otinga tohutoro
Tautuhinga C Ko te wa pupuri Waikawa Fumaric o te tihi nui i roto i te chromatogram whakatau ihirangi e rite ana ki te tihi o te tohutoro.
Ihirangi Wai (na KF) ≤1.0%
Maramatanga o te Otinga Ko te tikanga karekau he matūriki e kitea ana i roto i te 2% (w/v) o te whakamarama Methanol Solution
Wairewa toenga
Acetonitrile ≤410ppm
Ewaro ≤5000ppm
Dichloromethane ≤600ppm
Toluene ≤890ppm
Te toenga i runga i te mura ≤0.10%
Nga Korewa Taamaha ≤20ppm
Nga Taonga Paanga  
PMPA ≤1.0%
PMPA Anhydride ≤0.75%
Phenyl PMPA kotahi ≤1.0%
Tetahi poke kore i tohua ≤0.15%
Nga poke katoa ≤2.0%
Isomer ≤1.0%
Te ihirangi o te Waikawa Fumaric 9.0%~13.0% (i runga i te tikanga kore)
Nga Tepe Microbial
Tatau Moroiti Aerobic Tapeke ≤1000CFU/g
Tatau Rewena me nga Maaka ≤100CFU/g
Escherichia Coli Kei te ngaro
Te whakamatautau 98.0%~102.0% (i runga i te waikore me te whakarewa-kore)
Paerewa Whakamatau Paerewa hinonga

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.

Painga:

1

FAQ:

Taupānga:

Tenofovir Alafenamide Hemifumarate (TAF, GS-7340 hemifumarate), CAS 1392275-56-7, he nucleotide reverse transcriptase inhibitor (NRTIs) me te prodrug pukapuka o Tenofovir (TFV).Ma te aukati i te whakamuri transcriptase, ka aukati te TAF i te mate HIV kia nui haere, ka taea te whakaiti i te nui o te HIV i roto i te tinana.Ko te Tenofovir alafenamide he prodrug, ko te tikanga he rongoa kore mahi.I roto i te tinana, ka huri te tenofovir alafenamide ki Tenofovir diphosphate (TFV-DP).I whakaaetia a Tenofovir Alafenamide Fumarate i te marama o Noema 2015 mo te maimoatanga o te HIV-1.

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