tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7 Atazanavir Intermediate
Kaihanga Kaihanga Atazanavir Related Intermediates
Moc-L-Tert-Leucine CAS 162537-11-3
4-(2-Pyridyl)benzaldehyde CAS 127406-56-8
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7
Atazanavir CAS 198904-31-3
Atazanavir Sulfate CAS 229975-97-7
Ingoa matū | tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate |
Nga kupu taurite | 1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine |
Tau CAS | 198904-85-7 |
Tau CAT | RF-PI381 |
Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
Tātai rāpoi | C17H21N3O2 |
Taumaha rāpoi | 299.37 |
Te Whakarewa | 74.0~77.0℃(marama) |
Kiato | 1.117±0.06 g/cm3 |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura Kowhai Maama |
Ngaronga i te whakamaroke | ≤0.50% |
Maamaa | ≥98.0% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Atazanavir |
Mōkī: Pounamu, Peeke konumohe konumohe, Paera Kaata, 25kg / Paera, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama, i te makuku.
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate (CAS: 98904-85-7) he takawaenga i hangaia i te wa o te whakaputanga o nga aukati protease antiviral.He takawaenga o Atazanavir.Ko te Atazanavir he aukati o te HIV-1 protease (EC50=2.6 nM).I roto i nga pūtau taratahi, he taapiri ki nga paanga pareketo whakahiato ka honoa ki etahi atu raau taero antiretroviral.Ko te mutunga, ka whakamahia i roto i te vivo i roto i te rongoa whakakotahi mo te mate HIV-1.