tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7 Purity >98.0% (HPLC) Palbociclib Intermediate Factory
Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-kotahi CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4
Ingoa matū | tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate |
Nga kupu taurite | 1-Boc-4-(6-Nitro-3-Pyridyl)piperazine;4-(6-Nitro-3-pyridinyl)-1-Piperazinecarboxylic Acid tert-Butyl Ester;tert-Butyl 4-(6-Nitro-3-Pyridinyl)-1-Piperazinecarboxylate |
Tau CAS | 571189-16-7 |
Tau CAT | RF-PI1850 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C14H20N4O4 |
Taumaha rāpoi | 308.33 |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Parauri Maama ki te Paura Paraone |
Te Maama / Tikanga Tatauria | >98.0% (HPLC) |
LCMS | E rite ana ki te Hanganga |
Ngaronga i te whakamaroke | <1.00% |
Nga poke katoa | <2.00% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Palbociclib (CAS: 571190-30-2) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate (CAS: 571189-16-7) he takawaenga o Palbociclib (CAS: 571190-30-2).Ko Palbociclib (e mohiotia ana ko te nama puhui PD-0332991) he rongoa whakamatautau mo te maimoatanga o te mate pukupuku uma e whakawhanakehia ana e Pfizer.He aukati whiriwhiringa o nga kinases cyclin-dependent CDK4 me CDK6.Ka aukati a Palbociclib i te haere whakamua o te huringa pūtau mai i te wahanga G1 ki te S ma te aukati i te retinoblastoma (RB) phosphorylation CDK4/6.Kua whakamahia te Palbociclib mo te maimoatanga o te HER2 kino, te kaikawe estrogen (ER) te mate pukupuku uma metastatic pai.