TTBB CAS 124750-51-2 Purity >96.0% (HPLC) Irbesartan Intermediate Factory
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Ingoa matū | 5-(4'-Bromomethyl-1,1'-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazol |
Nga kupu taurite | TTBB;BBTT;5-[4'-Bromomethyl-(1,1'-Biphenyl)-2-yl]-1-Triphenylmethyltetrazol;N-(Triphenylmethyl)-5-(4'-Bromomethylbiphenyl-2-yl-)tetrazol;Olmesartan poke 12;Losartan Bromo N1-Trityl poke |
Tau CAS | 124750-51-2 |
Tau CAT | RF-PI1878 |
Tūnga Taonga | I roto i te Raarangi, Te Whakaputa Whakanui 150MT / Tau |
Tātai rāpoi | C33H25BrN4 |
Taumaha rāpoi | 557.48 |
Te Whakarewa | 152.0~155.0℃ |
Kiato | 1.28±0.10 g/cm3 |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te paura tata ma |
Te Maama / Tikanga Tatauria | >96.0% (HPLC) |
Ngaronga i te whakamaroke | <0.50% |
Te poke A | <2.00% (HPLC) 5-(4-Methyl-1,1-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazol |
Te poke B | <2.00% 5-(4'.4'-Dibromomethyl-1,1-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazol |
Spectrum Infrared | He rite ki te Hanganga |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Irbesartan (CAS: 138402-11-6);Olmesartan Medoxomil poke |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
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5-(4'-Bromomethyl-1,1'-Biphenyl-2-yl)-1-Triphenylmethyl-1H-Tetrazole (TTBB) (CAS: 124750-51-2) he takawaenga o Irbesartan (CAS: 138402-11 -6).Ka whakamahia a Irbesartan mo te maimoatanga o te whakaheke toto, me te nephropathy mate huka me te piki o te serum creatinine me te proteinuria (> 300 mg / ra) i nga turoro me te mate huka momo 2 me te whakaheke toto.Ka whakamahia ano a Irbesartan hei kaihoko raina tuarua i roto i te maimoatanga o nga conges.Ko Irbesartan te angiotensin II receptor antagonist e whakamahia ana mo te maimoatanga o te whakaheke toto.I whakawhanakehia e Sanofi Research (inaianei he wahanga o Sanofi-Aventis).Kei te hokohoko tahi e Sanofi-Aventis me Bristol-Myers Squibb i raro i nga ingoa hokohoko Aprovel, Karvea, me Avapro.
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