MOPSO CAS 68399-77-9 Purity >99.0% (Titration) Biological Buffer Ultra Pure Grade Factory

MOPSO Free Acid (CAS: 68399-77-9) is a biological buffer also referred to as a second generation Good′s buffer which displays improved solubility compared to traditional Good′s buffers. It is a zwitterionic, morpholinic buffer, structurally similar to MOPS. It is commonly used for cell culture media, as a running buffer in electrophoresis, and for protein purification with chromatography. Due to low ionic mobility, MOPSO is regarded as an excellent buffer for use in capillary electrochromatography. MOPSO lacks the ability to form a complex with most metal ions and is recommended for use as a non-coordinating buffer in solutions with metal ions. MOPSO also interacts with the peptide backbone of bovine serum albumin (BSA) to stabilize BSA against thermal denaturation. The pKa of MOPSO is 6.9 which make it an ideal candidate for buffer formulations which require a pH slightly below physiological to maintain a stable environment in solution. MOPSO is considered to be non-toxic to culture cell lines and provides high-solution clarity. MOPSO can be used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents. MOPSO Free Acid can be mixed with MOPSO Sodium Salt to acquire desired pH. Alternatively, it can be titrated with sodium hydroxide to attain desired pH.