1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0 Purità >98.0% (HPLC) Fabbrika Intermedja ta' Almotriptan Malate
Ruifu Chemical Supply Almotriptan Malate Intermedji:
Almotriptan Malate CAS 181183-52-8
1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)metil]anilina CAS 334981-10-1
1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0
4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9
Isem Kimiku | 1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine |
Sinonimi | N-[(4-Nitrophenyl)-methylsulfonyl]pyryolidine;1-((4-Nitrobenzyl)sulfonyl)pyrrolidine |
Numru CAS | 340041-91-0 |
Numru tal-KAT | RF-PI1959 |
Status tal-istokk | Fil-Ħażna, Skala ta' Produzzjoni Sa Tunnellati |
Formula Molekulari | C11H14N2O4S |
Piż Molekulari | 270.30 |
Brand | Ruifu Kimika |
Oġġett | Speċifikazzjonijiet |
Purità / Metodu ta 'Analiżi | >98.0% (HPLC) |
Telf fuq Tnixxif | <1.00% |
Standard tat-Test | Standard tal-Intrapriża |
Użu | Intermedju ta' Almotriptan Malate (CAS: 181183-52-8) |
Pakkett: Flixkun, borża tal-fojl tal-aluminju, 25kg/Drum tal-Kartun, jew skont il-ħtieġa tal-klijent
Kundizzjoni tal-Ħżin:Aħżen f'kontenituri ssiġillati f'post frisk u niexef;Ipproteġi mid-dawl u l-umdità
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1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine (CAS: 340041-91-0) huwa intermedju fil-Preparazzjoni ta 'Almotriptan Malate (CAS: 181183-52-8).Almotriptan Malate huwa agonist tas-sottotipi tar-riċetturi tas-serotonin (5-HT) 5-HT1Bu 5-HT1D(IC50s=12 u 13 nM, rispettivament, f'assaġġ ta' rabta tar-radjuligand).Almotriptan Malate (LAS 31416) huwa agonist selettiv tar-riċettur 5-hydroxytryptamine1B/1D (5-HT1B/1D), użat għat-trattament ta 'attakki ta' Emigranja fl-adulti.Almotriptan, imqiegħed fis-suq fl-2000, għandu l-ogħla bijodisponibilità orali fost it-triptani kollha.Huwa metabolizzat kemm minn MAO-A kif ukoll minn CYP3A4, għalhekk għandu profil ta' effetti sekondarji aktar favorevoli meta mqabbel ma' Sumatriptan.