CAS 361440-67-7 Purità > 98.5% (HPLC) Fabbrika
Intermedji Relatati mal-Provvista Kimika Ruifu
CAS 361442-04-8
CAS 945667-22-1
(R)-1-Boc-3-Aminopiperidine CAS 188111-79-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
Boc-3-Hydroxy-1-Adamantyl-D-Glycine CAS 361442-00-4
(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo [3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester CAS 361440-67-7
2-(3-Idrossi-1-Adamantyl)-2-Aċidu Ossoacetic CAS 709031-28-7
Isem Kimiku | (1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester |
Sinonimi | N-Boc-L-cis-4,5-Methanoprolineamide;N-Boc-cis-4,5-Methano-L-Prolinamide;tert-Butil (1S,3S,5S)-3-Carbamoyl-2-Azabicyclo[3.1.0]hexane-2-Carboxylate |
Numru CAS | 361440-67-7 |
Numru tal-KAT | RF-PI1990 |
Status tal-istokk | Fil-Ħażna, Skala ta' Produzzjoni Sa Tunnellati |
Formula Molekulari | C11H18N2O3 |
Piż Molekulari | 226.27 |
Punt tat-togħlija | 388.9±21.0℃ |
Densità | 1.228 |
Brand | Ruifu Kimika |
Oġġett | Speċifikazzjonijiet |
Dehra | Trab abjad |
Purità / Metodu ta 'Analiżi | >98.5% (HPLC) |
Telf fuq Tnixxif | <0.50% |
Residwu mat-Tqabbid | <0.20% |
Impuritajiet Individwali | <1.00% |
Impuritajiet Totali | <1.50% |
Standard tat-Test | Standard tal-Intrapriża |
Użu | Intermedju tal-API (CAS: 361442-04-8) |
Pakkett: Flixkun, borża tal-fojl tal-aluminju, 25kg/Drum tal-Kartun, jew skont il-ħtieġa tal-klijent
Kundizzjoni tal-Ħżin:Aħżen f'kontenituri ssiġillati f'post frisk u niexef;Ipproteġi mid-dawl u l-umdità
![1](https://a395.goodao.net/uploads/15.jpg)
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(1S,3S,5S)-3-(Aminocarbonyl)-2-Azabicyclo[3.1.0]hexane-2-Carboxylic Acid tert-Butyl Ester (CAS: 361440-67-7) huwa intermedju ta' API (CAS: 361442) -04-8).(CAS: 361442-04-8) huwa ipogliċemiku orali (mediċina kontra d-dijabete) tal-klassi ta 'mediċini inibitur dipeptidyl peptidase-4 (DPP-4).L-iżvilupp bikri kien biss minn Bristol-Myers Squibb;fl-2007 AstraZeneca ingħaqdet ma 'Bristol-Myers Squibb biex tiżviluppa flimkien il-kompost finali u tikkollabora fuq il-kummerċjalizzazzjoni tal-mediċina.F'Ġunju 2008, tħabbar li Onglyza se jkun l-isem kummerċjali li taħtu se jiġi kkummerċjalizzat.API (CAS: 361442-04-8) jintuża bħala monoterapija jew flimkien ma 'mediċini oħra għat-trattament tad-dijabete tat-tip 2.Jiġi assorbit malajr wara amministrazzjoni orali u għandu profil farmakokinetiku kompatibbli ma' dożaġġ ta' darba kuljum.Huwa għandu r-rwol billi jinibixxi d-degradazzjoni tal-GLP-l.GLP-I huwa l-ormoni prodotti b'mod naturali fl-imsaren wara li tieħu l-ikel.
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CAS 361442-04-8 Purità > 99.0% (HPLC) API
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CAS 945667-22-1 Purità > 99.0% (HPLC) API
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CAS 361440-67-7 Purità > 98.5% (HPLC) Fabbrika
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