Palbociclib Intermedju CAS 1013916-37-4 Purità > 99.0% (HPLC) Fabbrika Kwalità Għolja
Ruifu Chemical Supply Palbociclib Intermedji Relatati:
Palbociclib CAS 571190-30-2
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5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
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6-Bromo-2-Chloro-8-Cyclopentil-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Kloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4
Isem Kimiku | 2-Kloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one |
Sinonimi | 2-Chloro-8-Cyclopentyl-5-Methylpyrido[2,3-d]pyrimidin-7(8H)-one;Palbociclib Intermedju 2 |
Numru CAS | 1013916-37-4 |
Numru tal-KAT | RF-PI1847 |
Status tal-istokk | Fil-Ħażna, Skala ta' Produzzjoni Sa Tunnellati |
Formula Molekulari | C13H14ClN3O |
Piż Molekulari | 263.72 |
Solubilità fl-Ilma | Ftit Solubbli fl-Ilma |
Brand | Ruifu Kimika |
Oġġett | Speċifikazzjonijiet |
Dehra | Trab Isfar Ftit |
Purità / Metodu ta 'Analiżi | >99.0% (HPLC) |
Umdità (KF) | <0.50% |
Residwu mat-Tqabbid | <0.20% |
Impuritajiet Totali | <1.00% |
Standard tat-Test | Standard tal-Intrapriża |
Użu | Intermedju ta' Palbociclib (CAS: 571190-30-2) |
Pakkett: Flixkun, borża tal-fojl tal-aluminju, 25kg/Drum tal-Kartun, jew skont il-ħtieġa tal-klijent
Kundizzjoni tal-Ħżin:Aħżen f'kontenituri ssiġillati f'post frisk u niexef;Ipproteġi mid-dawl u l-umdità
2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (CAS: 1013916-37-4) jintuża bħala intermedju farmaċewtiku ta' Palbociclib (CAS: 571190-30) -2).Palbociclib huwa mediċina għat-trattament ta 'kanċer tas-sider ER-pożittiv u HER2-negattiv żviluppat.Huwa inibitur selettiv tal-kinażi li jiddependu fuq iċ-ċiklin CDK4 u CDK6.Palbociclib kien l-ewwel inibitur CDK4/6 li ġie approvat bħala terapija tal-kanċer minn kwalunkwe organizzazzjoni, u minn Diċembru 2017 ġie preskritt aktar minn 90,000 darba.